Vascular mechanotransduction

MJ Davis, S Earley, YS Li, S Chien - Physiological reviews, 2023 - journals.physiology.org
This review aims to survey the current state of mechanotransduction in vascular smooth
muscle cells (VSMCs) and endothelial cells (ECs), including their sensing of mechanical …

[HTML][HTML] Critical power: an important fatigue threshold in exercise physiology

DC Poole, M Burnley, A Vanhatalo… - Medicine and science …, 2016 - ncbi.nlm.nih.gov
The hyperbolic form of the power-duration relationship is rigorous and highly conserved
across species, forms of exercise and individual muscles/muscle groups. For modalities …

Cardiovascular consequences of metabolic syndrome

JD Tune, AG Goodwill, DJ Sassoon, KJ Mather - Translational Research, 2017 - Elsevier
The metabolic syndrome (MetS) is defined as the concurrence of obesity-associated
cardiovascular risk factors including abdominal obesity, impaired glucose tolerance …

[HTML][HTML] Red blood cells in sports: effects of exercise and training on oxygen supply by red blood cells

H Mairbäurl - Frontiers in physiology, 2013 - frontiersin.org
During exercise the cardiovascular system has to warrant substrate supply to working
muscle. The main function of red blood cells in exercise is the transport of O2 from the lungs …

[HTML][HTML] Characterization and modulation of systemic inflammatory response to exhaustive exercise in relation to oxidative stress

K Suzuki, T Tominaga, RT Ruhee, S Ma - Antioxidants, 2020 - mdpi.com
Exhaustive exercise induces systemic inflammatory responses, which are associated with
exercise-induced tissue/organ damage, but the sources and triggers are not fully …

Postexercise hypotension and sustained postexercise vasodilatation: what happens after we exercise?

JR Halliwill, TM Buck, AN Lacewell… - Experimental …, 2013 - Wiley Online Library
New findings• What is the topic for this review? During the exercise recovery period, the
combination of centrally mediated decreases in sympathetic nerve activity with a reduced …

Comparison of large animal models for acute ischemic stroke: which model to use?

A Taha, J Bobi, R Dammers, RM Dijkhuizen, AY Dreyer… - Stroke, 2022 - Am Heart Assoc
Translation of acute ischemic stroke research to the clinical setting remains limited over the
last few decades with only one drug, recombinant tissue-type plasminogen activator …

Multiple common comorbidities produce left ventricular diastolic dysfunction associated with coronary microvascular dysfunction, oxidative stress, and myocardial …

O Sorop, I Heinonen, M Van Kranenburg… - Cardiovascular …, 2018 - academic.oup.com
Aims More than 50% of patients with heart failure have preserved ejection fraction
characterized by diastolic dysfunction. The prevalance of diastolic dysfunction is higher in …

[HTML][HTML] Glucose uptake by skeletal muscle within the contexts of type 2 diabetes and exercise: an integrated approach

NA Hulett, RL Scalzo, JEB Reusch - Nutrients, 2022 - mdpi.com
Type 2 diabetes continues to negatively impact the health of millions. The inability to
respond to insulin to clear blood glucose (insulin resistance) is a key pathogenic driver of …

Assessment of resistance vessel function in human skeletal muscle: guidelines for experimental design, Doppler ultrasound, and pharmacology

JK Limberg, DP Casey, JD Trinity… - American Journal …, 2020 - journals.physiology.org
The introduction of duplex Doppler ultrasound almost half a century ago signified a
revolutionary advance in the ability to assess limb blood flow in humans. It is now widely …