The construction of synthetic gene circuits in plants has been limited by a lack of orthogonal
and modular parts. Here, we implement a CRISPR (clustered regularly interspaced short …

Synthetic gene circuits can enable new cellular behaviours by integrating multiple input
signals into customisable genetic programs. However, gene circuit development in plants …

The CRISPRoff system was recently introduced as a programmable epigenetic memory
writer that can be used to silence genes in human cells. The system makes use of a dead …

Gene editing has already proved itself as an invaluable tool for the generation of mutants for
crop breeding, yet its ultimate impact on agriculture will depend on how crops generated by …

Phaeodactylum tricornutum (Pt) is a critical microbial cell factory to produce a wide spectrum
of marketable products including recombinant biopharmaceutical N-glycoproteins. N …

To face the challenges of climate change and sustainable food production, it is essential to
develop crop genome editing techniques to pinpoint key genes involved in abiotic stress …

With the recent shift in perspective in compacting diagnostic laboratories to recreate
miniaturised and portable diagnostic tools that can perform rapid, on-site detection, novel …

New breeding techniques, especially CRISPR/Cas, could facilitate the expansion and
diversification of molecular farming crops by speeding up the introduction of new traits that …

The flourishing plant science promotes the exploding number of data and the expansion of
toolkits. Plant synthetic biology is still in its early stages and requires more quantitative and …

Programmierbare Endonukleasen sind wirksame Werkzeuge für die Pflanzenforschung und
Biotechnologie-gestützte Pflanzenzüchtung. Das in der vorliegenden Arbeit entwickelte …