Pathophysiology of atherosclerosis
S Jebari-Benslaiman, U Galicia-García… - International journal of …, 2022 - mdpi.com
Atherosclerosis is the main risk factor for cardiovascular disease (CVD), which is the leading
cause of mortality worldwide. Atherosclerosis is initiated by endothelium activation and …
cause of mortality worldwide. Atherosclerosis is initiated by endothelium activation and …
ROS-triggered endothelial cell death mechanisms: Focus on pyroptosis, parthanatos, and ferroptosis
D Zheng, J Liu, H Piao, Z Zhu, R Wei, K Liu - Frontiers in immunology, 2022 - frontiersin.org
The endothelium is a single layer of epithelium covering the surface of the vascular system,
and it represents a physical barrier between the blood and vessel wall that plays an …
and it represents a physical barrier between the blood and vessel wall that plays an …
[HTML][HTML] Activation of Nrf2/HO-1 signaling: An important molecular mechanism of herbal medicine in the treatment of atherosclerosis via the protection of vascular …
Q Zhang, J Liu, H Duan, R Li, W Peng, C Wu - Journal of advanced …, 2021 - Elsevier
Abstract Introduction Recently, Nrf2/HO-1 has received extensive attention as the main
regulatory pathway of intracellular defense against oxidative stress and is considered an …
regulatory pathway of intracellular defense against oxidative stress and is considered an …
Metabolic syndrome and cardiovascular diseases: Going beyond traditional risk factors
JL Silveira Rossi, SM Barbalho… - Diabetes/metabolism …, 2022 - Wiley Online Library
Metabolic syndrome (MS) is a chronic non‐infective syndrome characterised clinically by a
set of vascular risk factors that include insulin resistance, hypertension, abdominal obesity …
set of vascular risk factors that include insulin resistance, hypertension, abdominal obesity …
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
Abstract 'Reactive oxygen species'(ROS) is an umbrella term for an array of derivatives of
molecular oxygen that occur as a normal attribute of aerobic life. Elevated formation of the …
molecular oxygen that occur as a normal attribute of aerobic life. Elevated formation of the …
[HTML][HTML] Reactive oxygen species-based nanomaterials for the treatment of myocardial ischemia reperfusion injuries
Interventional coronary reperfusion strategies are widely adopted to treat acute myocardial
infarction, but morbidity and mortality of acute myocardial infarction are still high …
infarction, but morbidity and mortality of acute myocardial infarction are still high …
Effects of tobacco cigarettes, e-cigarettes, and waterpipe smoking on endothelial function and clinical outcomes
Tobacco smoking is a leading cause of non-communicable disease globally and is a major
risk factor for cardiovascular disease (CVD) and lung disease. Importantly, recent data by …
risk factor for cardiovascular disease (CVD) and lung disease. Importantly, recent data by …
Exploiting the dynamics of the EPR effect and strategies to improve the therapeutic effects of nanomedicines by using EPR effect enhancers
J Fang, W Islam, H Maeda - Advanced drug delivery reviews, 2020 - Elsevier
The enhanced permeability and retention (EPR) effect is a unique phenomenon of solid
tumors that is related to their particular anatomical and pathophysiological characteristics …
tumors that is related to their particular anatomical and pathophysiological characteristics …
Targeting early atherosclerosis: a focus on oxidative stress and inflammation
P Marchio, S Guerra-Ojeda, JM Vila… - Oxidative medicine …, 2019 - Wiley Online Library
Atherosclerosis is a chronic vascular inflammatory disease associated to oxidative stress
and endothelial dysfunction. Oxidation of low‐density lipoprotein (LDL) cholesterol is one of …
and endothelial dysfunction. Oxidation of low‐density lipoprotein (LDL) cholesterol is one of …
Emerging roles of energy metabolism in ferroptosis regulation of tumor cells
X Yao, W Li, D Fang, C Xiao, X Wu, M Li… - Advanced …, 2021 - Wiley Online Library
Ferroptosis is a new form of regulated cell death, which is characterized by the iron‐
dependent accumulation of lethal lipid peroxides and involved in many critical diseases …
dependent accumulation of lethal lipid peroxides and involved in many critical diseases …