Drugs of abuse have very different acute mechanisms of action but converge on the brain's
reward pathways by producing a series of common functional effects after both acute and …

Interest in BDNF as an activity-dependent modulator of neuronal structure and function in
the adult brain has intensified in recent years. Localization of BDNF-TrkB to glutamate …

Mice experiencing repeated aggression develop a long-lasting aversion to social contact,
which can be normalized by chronic, but not acute, administration of antidepressant. Using …

Persistent changes in behavior and psychological function that occur as a function of
experience, such those associated with learning and memory, are thought to be due to the …

Brain‐derived neurotrophic factor (BDNF) has important functions in the development of the
nervous system and in brain plasticity‐related processes such as memory, learning, and …

Brain-derived neurotrophic factor (BDNF) is a critical growth factor involved in the maturation
of the CNS, including neuronal morphology and synapse refinement. Herein, we …

Brain derived neurotrophic factor (BDNF), a member of the neurotrophin family of structurally
related proteins that promote neuronal differentiation and survival during development [1, 2] …

Context Brain-derived neurotrophic factor (BDNF) plays a pivotal role in the pathophysiology
of suicidal behavior andBDNFlevels are decreased in the brain and plasma of suicide …

The main characteristics of cocaine addiction are compulsive drug use despite adverse
consequences and high rates of relapse during periods of abstinence. A current popular …

Chronic vulnerability to relapse is a formidable challenge for the treatment of drug addiction.
The neurobiological basis of relapse and its prevention has, therefore, attracted major …