Sleep matters: Neurodegeneration spectrum heterogeneity, combustion and friction ultrafine particles, industrial nanoparticle pollution, and sleep disorders—Denial is …

L Calderón-Garcidueñas, R Torres-Jardón… - Frontiers in …, 2023 - frontiersin.org
Sustained exposures to ubiquitous outdoor/indoor fine particulate matter (PM2. 5), including
combustion and friction ultrafine PM (UFPM) and industrial nanoparticles (NPs) starting in …

[HTML][HTML] TDP-43 and NEAT long non-coding RNA: Roles in neurodegenerative disease

D Sekar, D Tusubira, K Ross - Frontiers in Cellular Neuroscience, 2022 - frontiersin.org
Understanding and ameliorating neurodegenerative diseases represents a key challenge
for supporting the health span of the aging population. Diverse protein aggregates have …

Cognitive and behavioral involvement in ALS has been known for more than a century

S Zago, L Lorusso, EN Aiello, M Ugolini, B Poletti… - Neurological …, 2022 - Springer
Background Among clinicians and researchers, it is common knowledge that, in ALS,
cognitive and behavioral involvement within the spectrum of frontotemporal degenerations …

[HTML][HTML] Necroptosis in CNS diseases: Focus on astrocytes

EV Mitroshina, M Saviuk, MV Vedunova - Frontiers in Aging …, 2023 - frontiersin.org
In the last few years, necroptosis, a recently described type of cell death, has been reported
to play an important role in the development of various brain pathologies. Necroptosis is a …

Volumetric analysis of hippocampal subregions and subfields in left and right semantic dementia

AF Carlos, SD Weigand, JR Duffy, HM Clark… - Brain …, 2024 - academic.oup.com
Two variants of semantic dementia are recognized based on the laterality of temporal lobe
involvement: a left-predominant variant associated with verbal knowledge impairment and a …

Comprehensive analysis of co-expressed genes with TDP-43: prognostic and therapeutic potential in lung adenocarcinoma

H Zhang, J Lin, BH Yahaya - Journal of Cancer Research and Clinical …, 2024 - Springer
Background Transactivating DNA-binding protein 43 (TDP-43) is intimately associated with
tumorigenesis and progression by regulating mRNA splicing, transport, stability, and non …

Serum transactive response DNA binding protein 43 associates with poor short-term neurologic outcome after return of spontaneous circulation following cardiac …

Z Sun, D Yu, P Li, L Wang, Y Chen, X Wei, P Gong - Shock, 2023 - journals.lww.com
Objective To explore the association of serum transactive response DNA binding protein 43
(TDP-43) with 28-day poor neurologic outcome in patients with return of spontaneous …

Unravelling the mechanisms of motor neuron degeneration in relation to TDP-43 pathology in amyotrophic lateral sclerosis

E Van Schoor - 2022 - lirias.kuleuven.be
Amyotrophic lateral sclerosis (ALS) is a rare neurodegenerative disorder that leads over
time to a more and more severe loss of motor function. The reason for this loss of motor …