Repeated, episodic bouts of skeletal muscle contraction undertaken frequently as structured
exercise training are a potent stimulus for physiological adaptation in many organs …

Viewing metabolism through the lens of exercise biology has proven an accessible and
practical strategy to gain new insights into local and systemic metabolic regulation. Recent …

The human ageing process is universal, ubiquitous and inevitable. Every physiological
function is being continuously diminished. There is a range between two distinct phenotypes …

The health benefits of exercise are well-recognized and are observed across multiple organ
systems. These beneficial effects enhance overall resilience, healthspan and longevity. The …

Cardiorespiratory fitness (CRF) refers to the capacity of the circulatory and respiratory
systems to supply oxygen to skeletal muscle mitochondria for energy production needed …

Mounting evidence has firmly established that low levels of cardiorespiratory fitness (CRF)
are associated with a high risk of cardiovascular disease, all-cause mortality, and mortality …

There is evidence from human twin and family studies as well as mouse and rat selection
experiments that there are considerable interindividual differences in the response of …

It has been demonstrated that heart rate variability (HRV) is predictive of all-cause and
cardiovascular mortality using clinical ECG recordings. This is true for rest, exercise and …

Background/Aim Cardiorespiratory fitness (CRF) is a strong determinant of morbidity and
mortality. In athletes and the general population, it is established that high-intensity interval …

Preservation of aerobic fitness and skeletal muscle strength through exercise training can
ameliorate metabolic dysfunction and prevent chronic disease. These benefits are mediated …