Telomerase reverse transcriptase (TERT) and the noncoding telomerase RNA (TR) subunit
constitute the core of telomerase. Additional subunits are required for ribonucleoprotein …

The 7SK ribonucleoprotein (RNP) is a dynamic and multifunctional regulator of RNA
Polymerase II (RNAPII) transcription in metazoa. Comprised of the non-coding 7SK RNA …

The effects and underlying mechanisms of adolescent exposure to combined environmental
hazards on cognitive function remain unclear. Here, using a combined exposure model, we …

RNA modifications have recently emerged as an important regulatory layer of gene
expression. The most prevalent and reversible modification on messenger RNA (mRNA), N6 …

Rationale: Endothelial-to-mesenchymal transition (EndMT) is a fundamental biological
process in which endothelial cells lose their endothelial characteristics and acquire …

La and La-related proteins (LARPs) are characterized by a common RNA interaction
platform termed the La module. This structural hallmark allows LARPs to pervade various …

Retinal neovascularization (RNV), a pathological process shared among diabetic
retinopathy, retinopathy of prematurity and other retinopathies, has been widely studied, but …

Epitranscriptomics is the study of RNA base modifications, including functionally relevant
transcriptomic changes. Epitranscriptomics has been actively studied in recent years and …

In modern times, a notable trend toward delayed childbearing has been observed in most
developed countries. As a result, sperm aging and quality loss, as well as premature ovarian …

Natural modifications of cellular RNA include various chemical modifications, such as N6‐
methyladenosine (m6A), which enable the orderly metabolism and function of RNA …