Simple Summary Next-generation sequencing (NGS) is a powerful tool used in genomics
research. NGS can sequence millions of DNA fragments at once, providing detailed …

Currently, there are about 7000 identified rare diseases, together affecting 10% of the
population. However, fewer than 6% of all rare diseases have an approved treatment option …

Chickpea is an important leguminous crop with potential to provide dietary proteins to both
humans and animals. It also ameliorates soil nitrogen through biological nitrogen fixation …

The use of CRISPR/Cas9 as a genome-editing tool in various model organisms has
radically changed targeted mutagenesis. Here, we present a high-throughput targeted …

Abstract The Alzheimer's Disease Sequencing Project (ADSP) undertook whole exome
sequencing in 5,740 late-onset Alzheimer disease (AD) cases and 5,096 cognitively normal …

Whole‐genome resequencing (WGR) is a powerful method for addressing fundamental
evolutionary biology questions that have not been fully resolved using traditional methods …

There is a growing attention toward personalized medicine. This is led by a fundamental
shift from the 'one size fits all'paradigm for treatment of patients with conditions or …

Next-generation sequencing (NGS) technologies using DNA, RNA, or methylation
sequencing have impacted enormously on the life sciences. NGS is the choice for large …

With expanding applications of next-generation sequencing in medical genetics, increasing
computational methods are being developed to predict the pathogenicity of missense …

Genomic sequencing technologies have revolutionized mutation detection of the genetic
diseases in the past few years. In recent years, the third generation sequencing (TGS) has …