Single-cell phospho-specific flow cytometric analysis demonstrates biochemical and functional heterogeneity in human hematopoietic stem and progenitor …

KD Gibbs Jr, PM Gilbert, K Sachs… - Blood, The Journal …, 2011 - ashpublications.org
The low frequency of hematopoietic stem and progenitor cells (HSPCs) in human BM has
precluded analysis of the direct biochemical effects elicited by cytokines in these …

The long road to the thymus: the generation, mobilization, and circulation of T-cell progenitors in mouse and man

DA Zlotoff, BA Schwarz, A Bhandoola - Seminars in immunopathology, 2008 - Springer
The majority of T cells develop in the thymus. T-cell progenitors in the thymus do not self-
renew and so progenitor cells must be continuously imported from the blood into the thymus …

Chemokine-mobilized adult stem cells; defining a better hematopoietic graft

LM Pelus, S Fukuda - Leukemia, 2008 - nature.com
Stem cell research is currently focused on totipotent stem cells and their therapeutic
potential, however adult stem cells, while restricted to differentiation within their tissue or …

Tea nanoparticles for immunostimulation and chemo-drug delivery in cancer treatment

S Yi, Y Wang, Y Huang, L Xia, L Sun… - Journal of …, 2014 - ingentaconnect.com
Many health benefits have been associated with tea consumption. In an effort to elucidate
the source of these health benefits, numerous phytochemicals have been extracted from tea …

Granulocyte colony-stimulating factor treatment ameliorates liver injury and improves survival in rats with D-galactosamine-induced acute liver failure

L Zhang, W Kang, Y Lei, Q Han, G Zhang, Y Lv, Z Li… - Toxicology letters, 2011 - Elsevier
Only liver transplantation is currently available therapy for the patients with acute liver failure
(ALF). This study was designed to determine whether administration of granulocyte colony …

[HTML][HTML] The efficacy of intrauterine instillation of granulocyte colony-stimulating factor in infertile women with a thin endometrium: A pilot study

D Lee, JD Jo, SK Kim, BC Jee… - Clinical and experimental …, 2016 - ncbi.nlm.nih.gov
Objective The study aimed to investigate the efficacy of intrauterine instillation of granulocyte
colony-stimulating factor (G-CSF) on the day of ovulation triggering or oocyte retrieval in …

Polysialic acid governs T-cell development by regulating progenitor access to the thymus

PM Drake, CM Stock, JK Nathan… - Proceedings of the …, 2009 - National Acad Sciences
Although the polysialyltransferase ST8Sia IV is expressed in both primary and secondary
human lymphoid organs, its product, polysialic acid (polySia), has been largely overlooked …

Mesenchymal stem cells in renal function recovery after acute kidney injury: use of a differentiating agent in a rat model

G La Manna, F Bianchi, M Cappuccilli… - Cell …, 2011 - journals.sagepub.com
Acute kidney injury (AKI) is a major health care condition with limited current treatment
options. Within this context, stem cells may provide a clinical approach for AKI. Moreover, a …

Stem cells, aging, niche, adhesion and Cdc42: a model for changes in cell-cell interactions and hematopoietic stem cell aging

H Geiger, A Koehler, M Gunzer - Cell Cycle, 2007 - Taylor & Francis
Hematopoietic stem cells from young and aged mice differ in their activity, and these
differences in the activity are mostly intrinsic to HSCs. We therefore refer to aged HSCs and …

The role of plasma granulocyte colony stimulating factor and bone marrow dysfunction after severe trauma

KM Cook, ZC Sifri, GM Baranski, AM Mohr… - Journal of the American …, 2013 - Elsevier
BACKGROUND: Bone marrow dysfunction is common in severely injured trauma patients,
with release of hematopoietic progenitor cells (HPC) into the peripheral blood. Granulocyte …