Radioactive main group and rare earth metals for imaging and therapy

TI Kostelnik, C Orvig - Chemical reviews, 2018 - ACS Publications
Radiometals possess an exceptional breadth of decay properties and have been applied to
medicine with great success for several decades. The majority of current clinical use …

Coordinating radiometals of copper, gallium, indium, yttrium, and zirconium for PET and SPECT imaging of disease

TJ Wadas, EH Wong, GR Weisman… - Chemical …, 2010 - ACS Publications
Molecular imaging is the visualization, characterization, and measurement of biological
processes at the molecular and cellular levels in humans and other living systems …

Applications of radiocomplexes with thiosemicarbazones and bis (thiosemicarbazones) in diagnostic and therapeutic nuclear medicine

GL Parrilha, RG dos Santos, H Beraldo - Coordination Chemistry Reviews, 2022 - Elsevier
Metallic radionuclides possess a variety of half-lives, emission types, energies, and
branching ratios, making it possible to apply them as diagnostic and/or therapeutic agents …

In vivo targeting and positron emission tomography imaging of tumor vasculature with 66Ga-labeled nano-graphene

H Hong, Y Zhang, JW Engle, TR Nayak, CP Theuer… - Biomaterials, 2012 - Elsevier
The goal of this study was to employ nano-graphene for tumor targeting in an animal tumor
model, and quantitatively evaluate the pharmacokinetics and tumor targeting efficacy …

Unconventional nuclides for radiopharmaceuticals

JP Holland, MJ Williamson, JS Lewis - Molecular imaging, 2010 - journals.sagepub.com
Rapid and widespread growth in the use of nuclear medicine for both diagnosis and therapy
of disease has been the driving force behind burgeoning research interests in the design of …

A Triazacyclononane‐Based Bifunctional Phosphinate Ligand for the Preparation of Multimeric 68Ga Tracers for Positron Emission Tomography

J Notni, P Hermann, J Havlíčková… - … A European Journal, 2010 - Wiley Online Library
For application in positron emission tomography (PET), PrP9, a N, N′, N′′‐trisubstituted
triazacyclononane with methyl (2‐carboxyethyl) phosphinic acid pendant arms, was …

A Step-by-Step Guide for the Novel Radiometal Production for Medical Applications: Case Studies with 68Ga, 44Sc, 177Lu and 161Tb

Z Talip, C Favaretto, S Geistlich, NP Meulen - Molecules, 2020 - mdpi.com
The production of novel radionuclides is the first step towards the development of new
effective radiopharmaceuticals, and the quality thereof directly affects the preclinical and …

Preparation of 66Ga-and 68Ga-labeled Ga (III)-deferoxamine-folate as potential folate-receptor-targeted PET radiopharmaceuticals

CJ Mathias, MR Lewis, DE Reichert, R Laforest… - Nuclear medicine and …, 2003 - Elsevier
A folate-receptor-targeting radiopharmaceutical, Ga (III)-deferoxamine-folate (Ga-DF-Folate),
was radiolabeled with two positron-emitting isotopes of gallium, cyclotron-produced 66Ga …

Copper, gallium and zirconium positron emission tomography imaging agents: The importance of metal ion speciation

LE McInnes, SE Rudd, PS Donnelly - Coordination Chemistry Reviews, 2017 - Elsevier
Positron emission tomography (PET) is a medical diagnostic imaging technique that
requires administration of a β+-emitting radiotracer to a patient. Metal-based PET …

Radionuclide candidates for β+ γ coincidence PET: an overview

M Sitarz, JP Cussonneau, T Matulewicz… - Applied Radiation and …, 2020 - Elsevier
Following the advancement of the Positron Emission Tomography (PET), a novel technique
emerged which takes advantage of the gamma quanta emitted, in some cases, after the β+ …