The etiology of preeclampsia
Preeclampsia is one of the “great obstetrical syndromes” in which multiple and sometimes
overlapping pathologic processes activate a common pathway consisting of endothelial cell …
overlapping pathologic processes activate a common pathway consisting of endothelial cell …
Clinical, pathophysiologic, genetic, and therapeutic progress in primary bilateral macronodular adrenal hyperplasia
J Bertherat, I Bourdeau, L Bouys… - Endocrine …, 2023 - academic.oup.com
Patients with primary bilateral macronodular adrenal hyperplasia (PBMAH) usually present
bilateral benign adrenocortical macronodules at imaging and variable levels of cortisol …
bilateral benign adrenocortical macronodules at imaging and variable levels of cortisol …
The immune system in Cushing's syndrome
V Hasenmajer, E Sbardella, F Sciarra… - Trends in endocrinology …, 2020 - cell.com
Cushing's syndrome (CS), or chronic hypercortisolism, induces a variety of alterations in the
immune system, often leading to severe clinical complications such as sepsis and …
immune system, often leading to severe clinical complications such as sepsis and …
By what molecular mechanisms do social determinants impact cardiometabolic risk?
While it is well known from numerous epidemiologic investigations that social determinants
(socioeconomic, environmental, and psychosocial factors exposed to over the life-course) …
(socioeconomic, environmental, and psychosocial factors exposed to over the life-course) …
Long‐term health consequences of congenital adrenal hyperplasia
Congenital adrenal hyperplasia (CAH) caused by 21‐hydroxylase deficiency accounts for
95% of all CAH cases and is one of the most common inborn metabolic conditions. The …
95% of all CAH cases and is one of the most common inborn metabolic conditions. The …
Cortisol excess in patients with primary aldosteronism impacts left ventricular hypertrophy
C Adolf, A Köhler, A Franke, K Lang… - The Journal of …, 2018 - academic.oup.com
Context Primary aldosteronism (PA) represents the most frequent form of endocrine
hypertension. Hyperaldosteronism and hypercortisolism both induce excessive left …
hypertension. Hyperaldosteronism and hypercortisolism both induce excessive left …
Sodium handling and interaction in numerous organs
S Minegishi, FC Luft, J Titze… - American journal of …, 2020 - academic.oup.com
Salt (NaCl) is a prerequisite for life. Excessive intake of salt, however, is said to increase
disease risk, including hypertension, arteriosclerosis, heart failure, renal disease, stroke …
disease risk, including hypertension, arteriosclerosis, heart failure, renal disease, stroke …
[HTML][HTML] Levoketoconazole in the treatment of patients with Cushing's syndrome and diabetes mellitus: results from the SONICS phase 3 study
Background Cushing's syndrome (CS) is associated with numerous comorbidities, including
diabetes mellitus (DM). Levoketoconazole, an orally administered ketoconazole …
diabetes mellitus (DM). Levoketoconazole, an orally administered ketoconazole …
[HTML][HTML] Very low-calorie ketogenic diet: a potential application in the treatment of hypercortisolism comorbidities
A very low-calorie ketogenic diet (VLCKD) is characterized by low daily caloric intake (less
than 800 kcal/day), low carbohydrate intake (< 50 g/day) and normoproteic (1–1.5 g of …
than 800 kcal/day), low carbohydrate intake (< 50 g/day) and normoproteic (1–1.5 g of …
[HTML][HTML] Distinguishing low and high water consumers—A paradigm of disease risk
LE Armstrong, CX Muñoz, EM Armstrong - Nutrients, 2020 - mdpi.com
A long-standing body of clinical observations associates low 24-h total water intake (TWI=
water+ beverages+ food moisture) with acute renal disorders such as kidney stones and …
water+ beverages+ food moisture) with acute renal disorders such as kidney stones and …