Even with modern treatment, acromegaly is associated with a 2-to 3-fold increase in
mortality, mainly from vascular disease, which is probably a result of the long exposure of …

Pituitary adenomas often present with the symptoms of hormonal hypersecretion, and
although medical therapy is available for most hyperfunctioning states, it is not curative. As a …

Objectives Sleep apnoea has been consistently reported to occur in acromegaly. Both
obstructive apnoeas, in which apnoeas are due to intermittent obstruction of the upper …

Acromegalic cardiomyopathy is the leading cause of morbidity and all‐cause mortality in
patients with acromegaly. Though acromegaly is a rare condition, the associated …

Inherited cardiomyopathies (CMs) are a major cause of heart diseases in all age groups,
which severely burdens patients as well as their family members. Data from the past two …

Context Untreated acromegaly is associated with increased morbidity and mortality due to
malignant, cardiovascular, and cerebrovascular disorders. Effective treatment of acromegaly …

Objective Left ventricular (LV) hypertrophy and myocardial fibrosis are considered the main
pathological features of acromegalic cardiomyopathy. The aim of the study was to evaluate …

In patients with acromegaly, the exact incidence of thyroid disorders is still controversial and
less is known about the impact of disease activity and successful treatment. To address this …

Cardiovascular disease is claimed to be one of the most severe complications of
acromegaly, contributing significantly to mortality in this disease. In fact, an excess of growth …

Objectives Sleep apnoea has been consistently reported to occur in acromegaly. In
uncontrolled patients, the severity of sleep apnoea influences physical activity in the …