Human plasma proteome during normal pregnancy
The human plasma proteome is underexplored despite its potential value for monitoring
health and disease. Herein, using a recently developed aptamer-based platform, we profiled …
health and disease. Herein, using a recently developed aptamer-based platform, we profiled …
Genomic imprinting and its effects on postnatal growth and adult metabolism
SJ Millership, M Van de Pette, DJ Withers - Cellular and Molecular Life …, 2019 - Springer
Imprinted genes display parent-of-origin-specific expression with this epigenetic system of
regulation found exclusively in therian mammals. Historically, defined imprinted gene …
regulation found exclusively in therian mammals. Historically, defined imprinted gene …
Balanced gene dosage control rather than parental origin underpins genomic imprinting
A Weinberg-Shukron, R Ben-Yair, N Takahashi… - Nature …, 2022 - nature.com
Mammalian parental imprinting represents an exquisite form of epigenetic control regulating
the parent-specific monoallelic expression of genes in clusters. While imprinting …
the parent-specific monoallelic expression of genes in clusters. While imprinting …
Placental glycogen stores and fetal growth: insights from genetic mouse models
The placenta performs a range of crucial functions that support fetal growth during
pregnancy, including facilitating the supply of oxygen and nutrients to the fetus, removal of …
pregnancy, including facilitating the supply of oxygen and nutrients to the fetus, removal of …
The imprinted gene Delta like non-canonical Notch ligand 1 (Dlk1) is conserved in mammals, and serves a growth modulatory role during tissue development and …
GÁ Traustadóttir, LV Lagoni, LBS Ankerstjerne… - Cytokine & Growth …, 2019 - Elsevier
Delta like non-canonical Notch ligand 1 (Dlk1) is an imprinted gene, mainly known for its
involvement in adipogenesis, although it has been associated with many other stem …
involvement in adipogenesis, although it has been associated with many other stem …
[HTML][HTML] Pioneering studies on monogenic central precocious puberty
Pubertal timing in humans is determined by complex interactions including hormonal,
metabolic, environmental, ethnic, and genetic factors. Central precocious puberty (CPP) is …
metabolic, environmental, ethnic, and genetic factors. Central precocious puberty (CPP) is …
Exploring the causes and consequences of maternal metabolic maladaptations during pregnancy: lessons from animal models
AN Sferruzzi-Perri, J Lopez-Tello, T Napso, HEJ Yong - Placenta, 2020 - Elsevier
Pregnancy is a remarkable physiological state, during which the metabolic system of the
mother adapts to ensure that nutrients are made available for transfer to the fetus for growth …
mother adapts to ensure that nutrients are made available for transfer to the fetus for growth …
Role of genomic imprinting in mammalian development
Non-mendelian inheritance refers to the group of phenomena and observations related to
the inheritance of genetic information that cannot be merely explained by Mendel's laws of …
the inheritance of genetic information that cannot be merely explained by Mendel's laws of …
Chromosome 14q32. 2 imprinted region disruption as an alternative molecular diagnosis of Silver-Russell syndrome
S Geoffron, W Abi Habib… - The Journal of …, 2018 - academic.oup.com
Abstract Context Silver-Russell syndrome (SRS)(mainly secondary to 11p15 molecular
disruption) and Temple syndrome (TS)(secondary to 14q32. 2 molecular disruption) are …
disruption) and Temple syndrome (TS)(secondary to 14q32. 2 molecular disruption) are …
The long non-coding RNA Meg3 mediates imprinted gene expression during stem cell differentiation
S Farhadova, A Ghousein, F Charon… - Nucleic Acids …, 2024 - academic.oup.com
Abstract The imprinted Dlk1-Dio3 domain comprises the developmental genes Dlk1 and
Rtl1, which are silenced on the maternal chromosome in different cell types. On this parental …
Rtl1, which are silenced on the maternal chromosome in different cell types. On this parental …