[HTML][HTML] Paternal dietary ratio of n-6: n-3 polyunsaturated fatty acids programs offspring leptin expression and gene imprinting in mice

Q Shi, X Liu, X Fan, R Wang, K Qi - Frontiers in Nutrition, 2022 - frontiersin.org
Background This study determined the effects of the paternal dietary ratio of n-6: n-3
polyunsaturated fatty acids (PUFAs) on leptin expression in the offspring and associated …

The placental imprinted DLK1-DIO3 domain: a new link to prenatal and postnatal growth in humans

A Prats-Puig, G Carreras-Badosa, J Bassols… - American Journal of …, 2017 - Elsevier
Background The developmentally important DLK1-DIO3 imprinted domain on human
chromosome 14 is regulated by 2 differentially methylated regions, the intergenic …

Imprinted genes influencing the quality of maternal care

HDJ Creeth, GI McNamara, AR Isles… - Frontiers in …, 2019 - Elsevier
In mammals successful rearing imposes a cost on later reproductive fitness specifically on
the mother creating the potential for parental conflict. Loss of function of three imprinted …

[HTML][HTML] A pipeline for making 31P NMR accessible for small- and large-scale lipidomics studies

S Furse, HEL Williams, AJ Watkins, S Virtue… - Analytical and …, 2021 - Springer
Detailed molecular analysis is of increasing importance in research into the regulation of
biochemical pathways, organismal growth and disease. Lipidomics in particular is …

The evolution of genomic imprinting: Epigenetic control of mammary gland development and postnatal resource control

G Hanin, AC Ferguson‐Smith - Wiley Interdisciplinary Reviews …, 2020 - Wiley Online Library
Genomic imprinting is an epigenetically regulated process leading to gene expression
according to its parental origin. Imprinting is essential for prenatal growth and development …

[HTML][HTML] The origins of genomic imprinting in mammals

CA Edwards, N Takahashi, JA Corish… - Reproduction …, 2019 - CSIRO Publishing
Genomic imprinting is a process that causes genes to be expressed according to their
parental origin. Imprinting appears to have evolved gradually in two of the three mammalian …

Imprinted Dlk1 dosage as a size determinant of the mammalian pituitary gland

V Scagliotti, ML Vignola, T Willis, M Howard, E Marinelli… - Elife, 2023 - elifesciences.org
Co-regulated genes of the Imprinted Gene Network are involved in the control of growth and
body size, and imprinted gene dysfunction underlies human paediatric disorders involving …

[HTML][HTML] Dynamic expression of imprinted genes in the developing and postnatal pituitary gland

V Scagliotti, R Esse, TL Willis, M Howard, I Carrus… - Genes, 2021 - mdpi.com
In mammals, imprinted genes regulate many critical endocrine processes such as growth,
the onset of puberty and maternal reproductive behaviour. Human imprinting disorders (IDs) …

Circulating Delta-like homolog 1 (DLK1) at 36 weeks is correlated with birthweight and is of placental origin

TM MacDonald, SP Walker, R Hiscock, P Cannon… - Placenta, 2020 - Elsevier
Abstract Introduction Recently, Delta-like homolog 1 (DLK1) was identified as a potential
marker of small-for-gestational-age (SGA;< 10th centile) fetuses; mouse studies suggest …

[HTML][HTML] Identification of methylation changes associated with positive and negative growth deviance in Gambian infants using a targeted methyl sequencing approach …

CR Quilter, KM Harvey, J Bauer, BM Skinner… - FASEB …, 2021 - ncbi.nlm.nih.gov
Low birthweight and reduced height gain during infancy (stunting) may arise at least in part
from adverse early life environments that trigger epigenetic reprogramming that may favor …