Feto-placental unit: from development to function

A Covarrubias, M Aguilera-Olguín… - Advances in Maternal …, 2023 - Springer
The placenta is an intriguing organ that allows us to survive intrauterine life. This essential
organ connects both mother and fetus and plays a crucial role in maternal and fetal well …

Circulating Delta-like homolog 1 (DLK1) at 36 weeks is correlated with birthweight and is of placental origin

TM MacDonald, SP Walker, R Hiscock, P Cannon… - Placenta, 2020 - Elsevier
Abstract Introduction Recently, Delta-like homolog 1 (DLK1) was identified as a potential
marker of small-for-gestational-age (SGA;< 10th centile) fetuses; mouse studies suggest …

[HTML][HTML] Identification of methylation changes associated with positive and negative growth deviance in Gambian infants using a targeted methyl sequencing approach …

CR Quilter, KM Harvey, J Bauer, BM Skinner… - FASEB …, 2021 - ncbi.nlm.nih.gov
Low birthweight and reduced height gain during infancy (stunting) may arise at least in part
from adverse early life environments that trigger epigenetic reprogramming that may favor …

Pregnancy serum DLK1 concentrations are associated with indices of insulin resistance and secretion

CJ Petry, KA Burling, P Barker… - The Journal of …, 2021 - academic.oup.com
Context Delta like noncanonical notch ligand 1 (DLK1) is a paternally expressed imprinted
gene that encodes an epidermal growth factor repeat-containing transmembrane protein. A …

[HTML][HTML] Effects of Adipose Tissue-Specific Knockout of Delta-like Non-Canonical Notch Ligand 1 on Lipid Metabolism in Mice

X Lu, X Fang, J Mi, Y Liu, R Liu, G Li, Y Li… - International Journal of …, 2023 - mdpi.com
Delta-like non-canonical Notch ligand 1 (DLK1), which inhibits the differentiation of
precursor adipocytes, is a recognized marker gene for precursor adipocytes. Lipids play a …

Mitigation of Fetal Radiation Injury from Mid-Gestation Total-body Irradiation by Maternal Administration of Mitochondrial-Targeted GS-Nitroxide JP4-039

YL Wu, AG Christodoulou, JH Beumer… - Radiation …, 2024 - meridian.allenpress.com
Victims of a radiation terrorist event will include pregnant women and unborn fetuses.
Mitochondrial dysfunction and oxidative stress are key pathogenic factors of fetal radiation …

[HTML][HTML] Low maternal DLK1 levels at 26 weeks is associated with small for gestational age at birth

A Pham, D Mitanchez, A Forhan, L Perin… - Frontiers in …, 2022 - frontiersin.org
Detecting SGA (small for gestational age) during pregnancy improves the fetal and neonatal
prognosis. To date, there is no valid antenatal biomarker of SGA used in clinical practice …

Effects of maternal feed intake restriction during pregnancy on the expression of growth regulation, imprinting and epigenetic transcription-related genes in foetal …

X Li, Q Yan, S Tang, Z Tan, CJ Fitzsimmons… - Animal reproduction …, 2018 - Elsevier
Maternal nutrition during gestation is a leading factor of modifying the foetal epigenome and
phenotype for mammals. Imprinting genes have important roles in regulating foetal growth …

Pregnancy-induced cardiovascular pathologies: importance of structural components and lipids

L Aleksenko, IK Quaye - The American Journal of the Medical Sciences, 2020 - Elsevier
Pregnancy leads to adaptations for maternal and fetal energy needs. The cardiovascular
system bears the brunt of the adaptations as the heart and vessels enable nutrient supply to …

A Fanca knockout mouse model reveals novel Fancd2 function

Q Wang, J Liu, Y Zhong, D Li, Y Zhong, H Ying… - Biochemical and …, 2024 - Elsevier
Fanconi anemia (FA) is a genetically and clinically heterogenous inherited disorder.
Clinically, Fanca subtype patients exhibited milder phenotypes compared to Fancd2 …