Genomic imprinting is an epigenetic phenomenon by which the expression of certain genes
follows a parent-of-origin-specific pattern. The sub-proximal end of mouse Chr 6 contains an …

In pregnancy, elevated circulating levels of delta-like homolog 1 (DLK1) are required for the
increased fatty acid metabolism needed during gestation. According to new research, these …

L'empreinte parentale, mécanisme épigénétique qui permet l'expression mono-allélique de
certains gènes en fonction de leur origine parentale, joue un rôle important dans la …

Imprinted genes are primarily associated with prenatal biology but have also been shown to
substantially impact the post-natal brain and, its output, infant and adult behaviour. One …

Thesis template of the University of Helsinki Page 1 Association of DNA methylation at the
imprinted DLK1- DIO3 locus in placenta with assisted reproductive technology and subfertility …

Background Fetal growth restriction is a major determinant of perinatal morbidity and
mortality. The condition has no gold standard definition but a widely used proxy is delivery of …

Abstract BRCA-1 Associated Protein 1 (BAP1) is a nuclear deubiquitylase (DUB) frequently
inactivated by mutation in specific cancers including malignant pleural mesothelioma …

We thank Dr Da-Xin Wang et al. for their valuable comments regarding our publication
highlighting the role of Dlk1 in regulating myocardial fibrotic response. 1 The suggestion that …

As yet undiscovered rare variants are hypothesized to substantially influence an individual's
risk for common diseases and traits, but sequencing studies aiming to identify such variants …

Background: Fetal metabolic programming imposed by maternal obesity and impaired
glucose tolerance predisposes the offspring to metabolic disease and beta cell dysfunction …