A subpopulation of spikes predicts successful epilepsy surgery outcome

J Thomas, P Kahane, C Abdallah, T Avigdor… - Annals of …, 2023 - Wiley Online Library
Objective Epileptic spikes are the traditional interictal electroencephalographic (EEG)
biomarker for epilepsy. Given their low specificity for identifying the epileptogenic zone (EZ) …

Pathological and physiological high-frequency oscillations on electroencephalography in patients with epilepsy

H Ye, C Chen, SA Weiss, S Wang - Neuroscience Bulletin, 2024 - Springer
High-frequency oscillations (HFOs) encompass ripples (80 Hz–200 Hz) and fast ripples (200
Hz–600 Hz), serving as a promising biomarker for localizing the epileptogenic zone in …

Developmental atlas of phase-amplitude coupling between physiologic high-frequency oscillations and slow waves

K Sakakura, N Kuroda, M Sonoda, T Mitsuhashi… - Nature …, 2023 - nature.com
We investigated the developmental changes in high-frequency oscillation (HFO) and
Modulation Index (MI)–the coupling measure between HFO and slow-wave phase. We …

Recent advances in clinical electroencephalography

B Frauscher, AO Rossetti… - Current Opinion in …, 2024 - journals.lww.com
Recent advances in clinical electroencephalography : Current Opinion in Neurology Recent
advances in clinical electroencephalography : Current Opinion in Neurology Log in or Register …

Characterizing physiological high-frequency oscillations using deep learning

Y Zhang, H Chung, JP Ngo, T Monsoor… - Journal of neural …, 2022 - iopscience.iop.org
Objective. Intracranially-recorded interictal high-frequency oscillations (HFOs) have been
proposed as a promising spatial biomarker of the epileptogenic zone. However, HFOs can …

Modular pipeline for reconstruction and localization of implanted intracranial ECoG and sEEG electrodes

DJ Soper, D Reich, A Ross, P Salami, SS Cash, I Basu… - Plos one, 2023 - journals.plos.org
Implantation of electrodes in the brain has been used as a clinical tool for decades to
stimulate and record brain activity. As this method increasingly becomes the standard of …

The differing effects of sleep on ictal and interictal network dynamics in drug‐resistant epilepsy

S Hannan, J Thomas, K Jaber, C El Kosseifi… - Annals of …, 2024 - Wiley Online Library
Objective Sleep has important influences on focal interictal epileptiform discharges (IEDs),
and the rates and spatial extent of IEDs are increased in non‐rapid eye movement (NREM) …

Intrinsic and secondary epileptogenicity in focal cortical dysplasia type II

E Macdonald‐Laurs, AEL Warren, WS Lee… - …, 2023 - Wiley Online Library
Objective Favorable seizure outcome is reported following resection of bottom‐of‐sulcus
dysplasia (BOSD). We assessed the distribution of epileptogenicity and dysplasia in and …

Fast ripples reflect increased excitability that primes epileptiform spikes

SA Weiss, I Fried, J Engel Jr, MR Sperling… - Brain …, 2023 - academic.oup.com
The neuronal circuit disturbances that drive inter-ictal and ictal epileptiform discharges
remain elusive. Using a combination of extra-operative macro-electrode and micro-electrode …

SEEGAtlas: A framework for the identification and classification of depth electrodes using clinical images

R Zelmann, B Frauscher, RP Aro… - Journal of Neural …, 2023 - iopscience.iop.org
Objective. Accurate localization, classification, and visualization of intracranial electrodes
are fundamental for analyzing intracranial electrographic recordings. While manual contact …