Atopic dermatitis (AD) is a common inflammatory dermatosis affecting up to 30% of children
and 10% of adults worldwide. AD is primarily driven by an epidermal barrier defect which …

In the Gram-negative bacteria, many important virulence factors reach their destination via
two-step export systems, and they must traverse the periplasmic space before reaching the …

The ultimate goal of cutaneous wound healing is to reform a stratified epithelium to restore
the normal epidermal barrier, which involves the epithelial-to-mesenchymal transition (EMT) …

We have previously demonstrated the ability of the human vaginal strain Lactobacillus
crispatus 2029 (LC2029) for strong adhesion to cervicovaginal epithelial cells, expression of …

The microtubule cytoskeleton plays a critical role in a variety of cellular activities, and its
structures and functions have been extensively studied. However, little is known about cell …

Purpose Despite advances in gene therapy, the lack of safe and efficient gene delivery
systems limited the clinical effectiveness of gene therapy. Due to the inherent potential of …

Infection and invasion are the prerequisites for developing the disease symptoms in a host.
While the probable mechanism of host invasion and pathogenesis is known in many …

Cronobacter sakazakii is an opportunistic Gram-negative pathogen that has been identified
as a causative agent of severe foodborne infections with a higher risk of mortality in …

Background Auditory neuropathy is a cause of hearing loss that has been studied in a
number of animal models. Signal transmission from hair cells to spiral ganglion neurons …

Simple Summary Mastitis is a common and important clinical disease in ruminants, resulting
in decreased milk production, infertility and delayed conception. If not treated promptly …