[HTML][HTML] Current strategies for exosome cargo loading and targeting delivery

H Zeng, S Guo, X Ren, Z Wu, S Liu, X Yao - Cells, 2023 - mdpi.com
Extracellular vesicles (EVs) such as ectosomes and exosomes have gained attention as
promising natural carriers for drug delivery. Exosomes, which range from 30 to 100 nm in …

STAT3-EMT axis in tumors: Modulation of cancer metastasis, stemness and therapy response

M Sadrkhanloo, M Entezari, S Orouei, M Ghollasi… - Pharmacological …, 2022 - Elsevier
Epithelial-to-mesenchymal transition (EMT) mechanism is responsible for metastasis of
tumor cells and their spread to various organs and tissues of body, providing undesirable …

[HTML][HTML] The use of RNA-based treatments in the field of cancer immunotherapy

M Chehelgerdi, M Chehelgerdi - Molecular Cancer, 2023 - Springer
Over the past several decades, mRNA vaccines have evolved from a theoretical concept to a
clinical reality. These vaccines offer several advantages over traditional vaccine techniques …

Tissue‐derived extracellular vesicles in cancers and non‐cancer diseases: present and future

SR Li, QW Man, X Gao, H Lin, J Wang… - Journal of …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) are lipid‐bilayer membrane structures secreted by most cell
types. EVs act as messengers via the horizontal transfer of lipids, proteins, and nucleic …

[HTML][HTML] Liquid biopsies based on DNA methylation as biomarkers for the detection and prognosis of lung cancer

P Li, S Liu, L Du, G Mohseni, Y Zhang, C Wang - Clinical epigenetics, 2022 - Springer
Lung cancer (LC) is the main cause of cancer-related mortality. Most LC patients are
diagnosed in an advanced stage when the symptoms are obvious, and the prognosis is …

[HTML][HTML] Advances and challenges in the treatment of lung cancer

Y Li, B Yan, S He - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Lung cancer accounts for a relatively high proportion of malignant tumors. As the most
prevalent type of lung cancer, non-small cell lung cancer (NSCLC) is characterized by high …

[HTML][HTML] Liquid biopsy and non-small cell lung cancer: are we looking at the tip of the iceberg?

L Bonanno, A Dal Maso, A Pavan, E Zulato… - British journal of …, 2022 - nature.com
The possibility to analyse the tumour genetic material shed in the blood is undoubtedly one
of the main achievements of translational research in the latest years. In the modern clinical …

[HTML][HTML] Tumor-derived small extracellular vesicles: potential roles and mechanism in glioma

X Guo, R Sui, H Piao - Journal of Nanobiotechnology, 2022 - Springer
Small extracellular vesicles (SEVs) are extracellular vesicles containing DNA, RNA, and
proteins and are involved in intercellular communication and function, playing an essential …

Towards artificial intelligence-enabled extracellular vesicle precision drug delivery

ZF Greenberg, KS Graim, M He - Advanced Drug Delivery Reviews, 2023 - Elsevier
Abstract Extracellular Vesicles (EVs), particularly exosomes, recently exploded into
nanomedicine as an emerging drug delivery approach due to their superior biocompatibility …

[HTML][HTML] Exosomal proteins and lipids as potential biomarkers for lung cancer diagnosis, prognosis, and treatment

MT Hsu, YK Wang, YJ Tseng - Cancers, 2022 - mdpi.com
Simple Summary Exosomes (or extracellular vesicles) are known to mediate intercellular
communication and to transmit molecular signals between cells. Molecules carried by …