Pain in women: a perspective review on a relevant clinical issue that deserves prioritization

R Casale, F Atzeni, L Bazzichi, G Beretta, E Costantini… - Pain and therapy, 2021 - Springer
Introduction Gender equity and gender medicine are opportunities not to be missed, and this
Expert Group Opinion Paper on pain in women aims to review the treatment of pain …

Prolactin and oxytocin: potential targets for migraine treatment

AK Szewczyk, S Ulutas, T Aktürk, L Al-Hassany… - The Journal of …, 2023 - Springer
Migraine is a severe neurovascular disorder of which the pathophysiology is not yet fully
understood. Besides the role of inflammatory mediators that interact with the …

PACAP induces light aversion in mice by an inheritable mechanism independent of CGRP

A Kuburas, BN Mason, B Hing, AS Wattiez… - Journal of …, 2021 - Soc Neuroscience
The neuropeptides CGRP (calcitonin gene-related peptide) and PACAP (pituitary adenylate
cyclase-activating polypeptide) have emerged as mediators of migraine, yet the potential …

A link between migraine and prolactin: the way forward

P Gazerani - Future science OA, 2021 - Taylor & Francis
Migraine is an incapacitating neurological disorder that predominantly affects women. Sex
and other hormones (eg, oxytocin, and prolactin) may play a role in sexual dimorphic …

The role of oxytocin, vasopressin, and their receptors at nociceptors in peripheral pain modulation

H Zheng, JY Lim, Y Kim, ST Jung, SW Hwang - Frontiers in …, 2021 - Elsevier
Oxytocin and vasopressin are neurohypophyseal hormones with sequence similarity and
play a central role in bodily homeostatic regulation. Pain is currently understood to be an …

A prolactin-dependent sexually dimorphic mechanism of migraine chronification

D Ikegami, E Navratilova, X Yue, A Moutal… - …, 2022 - journals.sagepub.com
Objective Determination of possible sex differences in mechanisms promoting migraine
progression and the contribution of prolactin and the prolactin long (PRLR-L) and short …

A new hypothesis linking oxytocin to menstrual migraine

VN Bharadwaj, F Porreca, RP Cowan… - … : The Journal of …, 2021 - Wiley Online Library
Objective To highlight the emerging understanding of oxytocin (OT) and oxytocin receptors
(OTRs) in modulating menstrual‐related migraine (MRM). Background MRM is highly …

Medication overuse headache

S Ashina, GM Terwindt, TJ Steiner, MJ Lee… - Nature Reviews …, 2023 - nature.com
Medication overuse headache (MOH) is a secondary headache disorder attributed to
overuse of acute headache medications by a person with an underlying headache disorder …

The role of prolactin/vasoinhibins in cardiovascular diseases

H Zhao, S Gong, Y Shi, C Luo, H Qiu… - Animal Models and …, 2023 - Wiley Online Library
Prolactin (PRL) is a polypeptide hormone that is mainly synthesized and secreted by the
lactotroph cells of the pituitary. There are two main isoforms of PRL: 23‐kDa PRL (named full …

Pituitary hormones are specifically expressed in trigeminal sensory neurons and contribute to pain responses in the trigeminal system

AH Hovhannisyan, H Son, J Mecklenburg… - Scientific reports, 2021 - nature.com
Abstract Trigeminal (TG), dorsal root (DRG), and nodose/jugular (NG/JG) ganglia each
possess specialized and distinct functions. We used RNA sequencing of two-cycle sorted …