Exosomal circular RNAs: a chief culprit in cancer chemotherapy resistance

X Guo, C Gao, DH Yang, S Li - Drug Resistance Updates, 2023 - Elsevier
Chemotherapy is one of the primary treatments for malignant tumors. However, the acquired
drug resistance hinders clinical efficacy and leads to treatment failure in most patients …

[HTML][HTML] NEAT1 as a competing endogenous RNA in tumorigenesis of various cancers: Role, mechanism and therapeutic potential

K Li, T Yao, Y Zhang, W Li, Z Wang - International journal of …, 2021 - ncbi.nlm.nih.gov
The nuclear paraspeckle assembly transcript 1 (NEAT1) is a long non-coding RNA (lncRNA)
that is upregulated in a variety of human cancer types. Increasing evidence has shown that …

[HTML][HTML] GLI1: a therapeutic target for cancer

JT Avery, R Zhang, RJ Boohaker - Frontiers in oncology, 2021 - frontiersin.org
GLI1 is a transcriptional effector at the terminal end of the Hedgehog signaling (Hh) pathway
and is tightly regulated during embryonic development and tissue patterning/differentiation …

[HTML][HTML] Osteoporosis in childhood cancer survivors: physiopathology, prevention, therapy and future perspectives

F Rossi, C Tortora, M Paoletta, MM Marrapodi… - Cancers, 2022 - mdpi.com
Simple Summary Anti-cancer treatments induced an increase in the childhood cancer
survival rate. However, they are responsible for several long-term side effects in childhood …

[HTML][HTML] Variant rs8400 enhances ALKBH5 expression through disrupting miR-186 binding and promotes neuroblastoma progression

Q Guan, H Lin, W Hua, L Lin, J Liu, L Deng… - Chinese Journal of …, 2023 - ncbi.nlm.nih.gov
Objective AlkB homolog 5 (ALKBH5) has been proven to be closely related to tumors.
However, the role and molecular mechanism of ALKBH5 in neuroblastomas have rarely …

[HTML][HTML] Intraoperative molecular imaging: 3rd biennial clinical trials update

P Bou-Samra, N Muhammad, A Chang… - … of biomedical optics, 2023 - spiedigitallibrary.org
Significance This third biennial intraoperative molecular imaging (IMI) conference shows
how optical contrast agents have been applied to develop clinically significant endpoints …

[HTML][HTML] Hopes on immunotherapy targeting B7-H3 in neuroblastoma

R Pulido, CE Nunes-Xavier - Translational Oncology, 2023 - Elsevier
Neuroblastoma is one of the most aggressive cancer forms in children, with highly
heterogenous clinical manifestations ranging from spontaneous regression to high …

[HTML][HTML] Novel role of immune-related non-coding RNAs as potential biomarkers regulating tumour immunoresponse via MICA/NKG2D pathway

J Zhang, Q Luo, X Li, J Guo, Q Zhu, X Lu, L Wei… - Biomarker …, 2023 - Springer
Major histocompatibility complex class I related chain A (MICA) is an important and stress-
induced ligand of the natural killer group 2 member D receptor (NKG2D) that is expressed in …

[HTML][HTML] A shortage of FTH induces ROS and sensitizes RAS-proficient neuroblastoma N2A cells to ferroptosis

R Lu, Y Jiang, X Lai, S Liu, L Sun, ZW Zhou - International journal of …, 2021 - mdpi.com
Ferroptosis, an iron-dependent form of programmed cell death, has excellent potential as an
anti-cancer therapeutic strategy in different types of tumors, especially in RAS-mutated ones …

Design, syntheses, theoretical calculations, MM-GBSA, potential anti-cancer and enzyme activities of novel Schiff base compounds

H Yalazan, D Koç, F Aydın Kose… - Journal of …, 2023 - Taylor & Francis
In this study, new Schiff base compounds (SB-F-OH, SB-Cl-OH and SB-Br-OH) were derived
from chalcone-derived amine compounds containing halogen groups and 4 …