Epidemiology and risk factors for invasive candidiasis

N Yapar - Therapeutics and clinical risk management, 2014 - Taylor & Francis
The number of immunosuppressive patients has increased significantly in recent years.
These patients are at risk for opportunistic infections, especially fungal infections …

[HTML][HTML] Morbidity and mortality of candidaemia in Europe: an epidemiologic meta-analysis

P Koehler, M Stecher, OA Cornely, D Koehler… - Clinical microbiology …, 2019 - Elsevier
Objectives Candidaemia is a serious hazard to hospitalized patients, but European
epidemiological data are restricted to national studies focusing on Northern Europe …

Impact of treatment strategy on outcomes in patients with candidemia and other forms of invasive candidiasis: a patient-level quantitative review of randomized trials

DR Andes, N Safdar, JW Baddley… - Clinical infectious …, 2012 - academic.oup.com
Abstract (See the Editorial Commentary by Clancy and Nguyen, on pages 1123–5.)
Background. Invasive candidiasis (IC) is an important healthcare-related infection, with …

PCR diagnosis of invasive candidiasis: systematic review and meta-analysis

T Avni, L Leibovici, M Paul - Journal of clinical microbiology, 2011 - Am Soc Microbiol
Invasive candidiasis (IC) is a significant cause of morbidity and mortality. Diagnosis relies on
culture-based methods, which lack sensitivity and delay diagnosis. We conducted a …

Epidemiology, species distribution, antifungal susceptibility, and outcome of candidemia across five sites in Italy and Spain

M Bassetti, M Merelli, E Righi… - Journal of clinical …, 2013 - Am Soc Microbiol
Candidemia has become an important bloodstream infection that is frequently associated
with high rates of mortality and morbidity, and its growing incidence is related to complex …

Direct MALDI-TOF mass spectrometry assay of blood culture broths for rapid identification of Candida species causing bloodstream infections: an observational study …

T Spanu, B Posteraro, B Fiori, T D'Inzeo… - Journal of clinical …, 2012 - Am Soc Microbiol
We evaluated the reliability of the Bruker Daltonik's MALDI Biotyper system in species-level
identification of yeasts directly from blood culture bottles. Identification results were …

[HTML][HTML] Risk factors and outcomes of candidemia caused by biofilm-forming isolates in a tertiary care hospital

M Tumbarello, B Fiori, EM Trecarichi, P Posteraro… - PloS one, 2012 - journals.plos.org
Background Very few data exist on risk factors for developing biofilm-forming Candida
bloodstream infection (CBSI) or on variables associated with the outcome of patients treated …

Invasive mycoses: diagnostic challenges

L Ostrosky-Zeichner - The American journal of medicine, 2012 - Elsevier
Despite the availability of newer antifungal drugs, outcomes for patients with invasive fungal
infections (IFIs) continue to be poor, in large part due to delayed diagnosis and initiation of …

[HTML][HTML] Early diagnosis of candidemia in intensive care unit patients with sepsis: a prospective comparison of (1→3)-β-D-glucan assay, Candida score, and …

B Posteraro, G De Pascale, M Tumbarello, R Torelli… - Critical care, 2011 - Springer
Introduction The culture-independent serum (1→ 3)-β-D-glucan (BG) detection test may
allow early diagnosis of invasive fungal disease, but its clinical usefulness needs to be firmly …

[HTML][HTML] Brazilian guidelines for the management of candidiasis–a joint meeting report of three medical societies: Sociedade Brasileira de Infectologia, Sociedade …

AL Colombo, T Guimarães, LFA Camargo… - The Brazilian Journal of …, 2013 - Elsevier
Candida infections account for 80% of all fungal infections in the hospital environment,
including bloodstream, urinary tract and surgical site infections. Bloodstream infections are …