Targeting drugs to tumours using cell membrane-coated nanoparticles

RH Fang, W Gao, L Zhang - Nature Reviews Clinical Oncology, 2023 - nature.com
Traditional cancer therapeutics, such as chemotherapies, are often limited by their non-
specific nature, causing harm to non-malignant tissues. Over the past several decades …

[HTML][HTML] Bacterial extracellular vesicles-based therapeutic strategies for bone and soft tissue tumors therapy

H Liu, H Zhang, Y Han, Y Hu, Z Geng, J Su - Theranostics, 2022 - ncbi.nlm.nih.gov
Bone and soft tissue tumors are complex mesenchymal neoplasms that seriously endanger
human health. Over the past decade, the relationship between microorganisms and human …

Cloaking mesoporous polydopamine with bacterial membrane vesicles to amplify local and systemic antitumor immunity

W Chen, Y Song, S Bai, C He, Z Guo, Y Zhu, Z Zhang… - ACS …, 2023 - ACS Publications
As adjuvants or antigens, bacterial membranes have been widely used in recent
antibacterial and antitumor research, but they are often injected multiple times to achieve …

Outer membrane vesicles: biogenesis, functions, and issues

R Juodeikis, SR Carding - Microbiology and Molecular Biology …, 2022 - Am Soc Microbiol
This review focuses on nonlytic outer membrane vesicles (OMVs), a subtype of bacterial
extracellular vesicles (BEVs) produced by Gram-negative organisms focusing on the …

[HTML][HTML] Microbial synthesis of Prussian blue for potentiating checkpoint blockade immunotherapy

D Wang, J Liu, C Wang, W Zhang, G Yang… - Nature …, 2023 - nature.com
Cancer immunotherapy is revolutionizing oncology. The marriage of nanotechnology and
immunotherapy offers a great opportunity to amplify antitumor immune response in a safe …

[HTML][HTML] Engineered bacterial extracellular vesicles for osteoporosis therapy

H Liu, M Li, T Zhang, X Liu, H Zhang, Z Geng… - Chemical Engineering …, 2022 - Elsevier
Osteoporosis (OP) is a systemic bone disease characterized by reduction of bone mass and
destruction of structure, which can easily lead to fragility fractures. Over the past decade, an …

[HTML][HTML] Biomimetic cell-derived nanocarriers in cancer research

E Soprano, E Polo, B Pelaz, P Del Pino - Journal of Nanobiotechnology, 2022 - Springer
Nanoparticles have now long demonstrated capabilities that make them attractive to use in
biology and medicine. Some of them, such as lipid nanoparticles (SARS-CoV-2 vaccines) or …

Genetically engineered cellular nanoparticles for biomedical applications

N Krishnan, FX Peng, A Mohapatra, RH Fang, L Zhang - Biomaterials, 2023 - Elsevier
In recent years, nanoparticles derived from cellular membranes have been increasingly
explored for the prevention and treatment of human disease. With their flexible design and …

Biomimetic and bioinspired nano‐platforms for cancer vaccine development

C Feng, P Tan, G Nie, M Zhu - Exploration, 2023 - Wiley Online Library
The advent of immunotherapy has revolutionized the treating modalities of cancer. Cancer
vaccine, aiming to harness the host immune system to induce a tumor‐specific killing effect …

Intestinal organoids and organoids extracellular vesicles for inflammatory bowel disease treatment

H Liu, J Sun, M Wang, S Wang, J Su, C Xu - Chemical Engineering Journal, 2023 - Elsevier
Inflammatory bowel disease (IBD), a chronic inflammatory disease of the gastrointestinal
tract, is characterized by abdominal pain, diarrhea, and bloody stools, posing a serious …