A bibliometric analysis of RNA methylation in diabetes mellitus and its complications from 2002 to 2022

W Zhang, S Zhang, C Dong, S Guo, W Jia… - Frontiers in …, 2022 - frontiersin.org
Background RNA methylation has emerged as an active research field in diabetes mellitus
(DM) and its complications, while few bibliometric analyses have been performed. We aimed …

NLRP3-mediated pyroptosis in diabetic nephropathy

J Wan, D Liu, S Pan, S Zhou, Z Liu - Frontiers in pharmacology, 2022 - frontiersin.org
Diabetic nephropathy (DN) is the main cause of end-stage renal disease (ESRD), which is
characterized by a series of abnormal changes such as glomerulosclerosis, podocyte loss …

Necrosulfonamide ameliorates intestinal inflammation via inhibiting GSDMD-medicated pyroptosis and MLKL-mediated necroptosis

W Yang, K Tao, Y Wang, Y Huang, C Duan… - Biochemical …, 2022 - Elsevier
Inflammatory bowel disease (IBD) is a chronic relapsing disorder of the gastrointestinal tract,
while the present therapeutic efficacy is insufficient. In recent years, numerous studies have …

[HTML][HTML] Apabetalone, a BET protein inhibitor, inhibits kidney damage in diabetes by preventing pyroptosis via modulating the P300/H3K27ac/PLK1 axis

M Wang, Z Huang, X Li, P He, H Sun, Y Peng… - Pharmacological …, 2024 - Elsevier
Many inflammatory disorders, including diabetic kidney disease (DKD), are associated with
pyroptosis, a type of inflammation-regulated cell death. The purpose of this work was to …

[HTML][HTML] Betaine alleviates cognitive impairment induced by homocysteine through attenuating NLRP3-mediated microglial pyroptosis in an m6A-YTHDF2-dependent …

ZJ Yang, SY Huang, KY Zhong, WG Huang, ZH Huang… - Redox Biology, 2024 - Elsevier
Dementia, with homocysteine (Hcy) as an important risk factor, is a severe public health
problem in the aging society. Betaine serves as a methyl donor and plays an important role …

N6-methyladenosine methylation in kidney injury

Q Wang, X Fan, Q Sheng, M Yang, P Zhou, S Lu… - Clinical …, 2023 - Springer
Multiple mechanisms are involved in kidney damage, among which the role of epigenetic
modifications in the occurrence and development of kidney diseases is constantly being …

[HTML][HTML] Novel insights into the interplay between m6A modification and programmed cell death in cancer

J Chen, M Ye, J Bai, C Hu, F Lu, D Gu… - International journal of …, 2023 - ncbi.nlm.nih.gov
Abstract N6-methyladenosine (m6A) methylation, the most prevalent and abundant RNA
modification in eukaryotes, has recently become a hot research topic. Several studies have …

[HTML][HTML] Protein acetylation and related potential therapeutic strategies in kidney disease

X Li, J Yu, Y Dong, X Shen, R Hou, M Xie, J Wei… - Pharmacological …, 2023 - Elsevier
Kidney disease can be caused by various internal and external factors that have led to a
continual increase in global deaths. Current treatment methods can alleviate but do not …

The role of m6A and m6Am RNA modifications in the pathogenesis of diabetes mellitus

D Benak, S Benakova, L Plecita-Hlavata… - Frontiers in …, 2023 - frontiersin.org
The rapidly developing research field of epitranscriptomics has recently emerged into the
spotlight of researchers due to its vast regulatory effects on gene expression and thereby …

RNA m6A methylation regulators in sepsis

L Zhu, H Zhang, X Zhang, L Xia - Molecular and Cellular Biochemistry, 2023 - Springer
Abstract N6-methyladenosine (m6A) modification is a class of epitope modifications that has
received significant attention in recent years, particularly in relation to its role in various …