[HTML][HTML] Antioxidative and anti-inflammatory activity of ascorbic acid

A Gęgotek, E Skrzydlewska - Antioxidants, 2022 - mdpi.com
Ascorbic acid, as a one of the basic exogenous vitamins, occurs in the body in the form of
ascorbate, known for its strong antioxidant and anti-inflammatory properties. The presented …

[HTML][HTML] ROS in cancer therapy: the bright side of the moon

B Perillo, M Di Donato, A Pezone, E Di Zazzo… - … & molecular medicine, 2020 - nature.com
Reactive oxygen species (ROS) constitute a group of highly reactive molecules that have
evolved as regulators of important signaling pathways. It is now well accepted that moderate …

Oxygen‐Vacancy‐Rich Piezoelectric BiO2−x Nanosheets for Augmented Piezocatalytic, Sonothermal, and Enzymatic Therapies

L Yang, B Tian, Y Xie, S Dong, M Yang… - Advanced …, 2023 - Wiley Online Library
Piezocatalytic therapy is a new‐emerging reactive oxygen species (ROS)‐enabled
therapeutic strategy that relies on built‐in electric field and energy‐band bending of …

Role of oxidative stress in reperfusion following myocardial ischemia and its treatments

M Xiang, Y Lu, L Xin, J Gao, C Shang… - Oxidative medicine …, 2021 - Wiley Online Library
Myocardial ischemia is a disease with high morbidity and mortality, for which reperfusion is
currently the standard intervention. However, the reperfusion may lead to further myocardial …

[HTML][HTML] Melatonin's impact on antioxidative and anti-inflammatory reprogramming in homeostasis and disease

DM Chitimus, MR Popescu, SE Voiculescu… - Biomolecules, 2020 - mdpi.com
There is a growing consensus that the antioxidant and anti-inflammatory properties of
melatonin are of great importance in preserving the body functions and homeostasis, with …

Simultaneous Fenton‐like Ion Delivery and Glutathione Depletion by MnO2‐Based Nanoagent to Enhance Chemodynamic Therapy

LS Lin, J Song, L Song, K Ke, Y Liu, Z Zhou… - Angewandte …, 2018 - Wiley Online Library
Chemodynamic therapy (CDT) utilizes iron‐initiated Fenton chemistry to destroy tumor cells
by converting endogenous H2O2 into the highly toxic hydroxyl radical (. OH). There is a …

[HTML][HTML] Activation of apoptosis signalling pathways by reactive oxygen species

M Redza-Dutordoir, DA Averill-Bates - Biochimica et Biophysica Acta (BBA) …, 2016 - Elsevier
Reactive oxygen species (ROS) are short-lived and highly reactive molecules. The
generation of ROS in cells exists in equilibrium with a variety of antioxidant defences. At low …

Targeting RIPK1 for the treatment of human diseases

A Degterev, D Ofengeim… - Proceedings of the …, 2019 - National Acad Sciences
RIPK1 kinase has emerged as a promising therapeutic target for the treatment of a wide
range of human neurodegenerative, autoimmune, and inflammatory diseases. This was …

[HTML][HTML] ABC transporters in cancer stem cells: beyond chemoresistance

RR Begicevic, M Falasca - International journal of molecular sciences, 2017 - mdpi.com
The efficacy of chemotherapy is one of the main challenges in cancer treatment and one of
the major obstacles to overcome in achieving lasting remission and a definitive cure in …

Magnetostrictive-piezoelectric-triggered nanocatalytic tumor therapy

M Ge, D Xu, Z Chen, C Wei, Y Zhang, C Yang… - Nano Letters, 2021 - ACS Publications
Magnetic-based theranostics feature a high efficiency, excellent tissue penetration, and
minimal damage to normal tissues, are noninvasive, and are widely used in the diagnosis …