The heat-shock proteins
S Lindquist, EA Craig - Annual review of genetics, 1988 - annualreviews.org
All organisms respond to heat by inducing the synthesis of a group of proteins called the
heat-shock proteins or hsps. The response is the most highly conserved genetic system …
heat-shock proteins or hsps. The response is the most highly conserved genetic system …
Ischemic cell death in brain neurons
P Lipton - Physiological reviews, 1999 - journals.physiology.org
This review is directed at understanding how neuronal death occurs in two distinct insults,
global ischemia and focal ischemia. These are the two principal rodent models for human …
global ischemia and focal ischemia. These are the two principal rodent models for human …
Selective vulnerability of the hippocampus in brain ischemia
R Schmidt-Kastner, TF Freund - Neuroscience, 1991 - Elsevier
Selective vulnerability of the hippocampus in brain ischemia - ScienceDirect Skip to main
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Brain ischemia and reperfusion: molecular mechanisms of neuronal injury
BC White, JM Sullivan, DJ DeGracia, BJ O'Neil… - Journal of the …, 2000 - Elsevier
Brain ischemia and reperfusion engage multiple independently-fatal terminal pathways
involving loss of membrane integrity in partitioning ions, progressive proteolysis, and …
involving loss of membrane integrity in partitioning ions, progressive proteolysis, and …
Induction of heat shock proteins for protection against oxidative stress
B Kalmar, L Greensmith - Advanced drug delivery reviews, 2009 - Elsevier
Heat shock proteins (Hsps) have been studied for many years and there is now a large body
of evidence that demonstrates the role of Hsp upregulation in tissue and cell protection in a …
of evidence that demonstrates the role of Hsp upregulation in tissue and cell protection in a …
The possibility of neurotoxicity in the hippocampus in major depression: a primer on neuron death
RM Sapolsky - Biological psychiatry, 2000 - Elsevier
A number of studies indicate that prolonged, major depression is associated with a selective
loss of hippocampal volume that persists long after the depression has resolved. This review …
loss of hippocampal volume that persists long after the depression has resolved. This review …
Stress and depression: possible links to neuron death in the hippocampus
AL Lee, WO Ogle, RM Sapolsky - Bipolar disorders, 2002 - Wiley Online Library
Recent intriguing reports have shown an association between major depression and
selective and persistent loss of hippocampal volume, prompting considerable speculation as …
selective and persistent loss of hippocampal volume, prompting considerable speculation as …
Hypoxia alters early gestation human cytotrophoblast differentiation/invasion in vitro and models the placental defects that occur in preeclampsia.
O Genbacev, R Joslin, CH Damsky… - The Journal of …, 1996 - Am Soc Clin Investig
During normal human pregnancy a subpopulation of fetal cytotrophoblast stem cells
differentiate and invade the uterus and its arterioles. In the pregnancy disease …
differentiate and invade the uterus and its arterioles. In the pregnancy disease …
Heat shock proteins as cellular lifeguards
M Jäättelä - Annals of medicine, 1999 - Taylor & Francis
Cells have developed complex ways to respond to various stresses. Interestingly, stresses
such as heat, ischaemia and radiation can induce different cellular responses depending on …
such as heat, ischaemia and radiation can induce different cellular responses depending on …
Kainic acid seizures in the rat
G Sperk - Progress in neurobiology, 1994 - Elsevier
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