Role of interleukin-6 in depressive disorder
Major depressive disorder (MDD), which is a leading psychiatric illness across the world,
severely affects quality of life and causes an increased incidence of suicide. Evidence from …
severely affects quality of life and causes an increased incidence of suicide. Evidence from …
Chronic stress and endothelial dysfunction: mechanisms, experimental challenges, and the way ahead
LD Sher, H Geddie, L Olivier… - American Journal …, 2020 - journals.physiology.org
Although chronic stress is an important risk factor for cardiovascular diseases (CVD) onset,
the underlying mechanisms driving such pathophysiological complications remain relatively …
the underlying mechanisms driving such pathophysiological complications remain relatively …
Antidepressant effect of taurine in chronic unpredictable mild stress-induced depressive rats
GF Wu, S Ren, RY Tang, C Xu, JQ Zhou, SM Lin… - Scientific reports, 2017 - nature.com
Depression, a psychiatric and dysthymic disorder, severely affects the learning, work and life
quality. The main pathogenesis of depression is associated with central nervous system …
quality. The main pathogenesis of depression is associated with central nervous system …
Inflammation and treatment-resistant depression from clinical to animal study: a possible link?
LF Almutabagani, RA Almanqour, JF Alsabhan… - Neurology …, 2023 - mdpi.com
The aim of this study was to investigate the relationship between treatment-resistant
depression (TRD) and inflammation in humans and experimental models. For the human …
depression (TRD) and inflammation in humans and experimental models. For the human …
Prefrontal cortical trkB, glucocorticoids, and their interactions in stress and developmental contexts
ET Barfield, SL Gourley - Neuroscience & Biobehavioral Reviews, 2018 - Elsevier
The tropomyosin/tyrosine receptor kinase B (trkB) and glucocorticoid receptor (GR) regulate
neuron structure and function and the hormonal stress response. Meanwhile, disruption of …
neuron structure and function and the hormonal stress response. Meanwhile, disruption of …
Metabolomics analysis of the antidepressant prescription Danzhi Xiaoyao Powder in a rat model of Chronic Unpredictable Mild Stress (CUMS)
Y Zhu, S Li, C Zhu, W Wang, W Zuo, X Qiu - Journal of ethnopharmacology, 2020 - Elsevier
Abstract Ethnopharmacological relevance Danzhi Xiaoyao Powder (DZXY) is a classical
prescription, that has been extensively used in traditional Chinese medicine (TMC) to treat …
prescription, that has been extensively used in traditional Chinese medicine (TMC) to treat …
[HTML][HTML] Synthesis and antidepressant-like effects of new 5-epi-incensole and 5-epi-incensole acetate in chronic unpredictable mild stress model of depression; …
In the current investigation, 5-epi-incensole (3) and 5-epi-incensole acetate (5) were
synthesized from the most potent anti-depressant constituents incensole (1) and incensole …
synthesized from the most potent anti-depressant constituents incensole (1) and incensole …
Antidepressant Effect of Alpha Lipoic Acid in Rats Exposed to Chronic Unpredictable Mild Stress: Putative Role of Neurotransmitters and 5HT3 Receptor
Depression is a neuropsychiatric disorder characterized by altered emotion and cognition.
Alpha lipoic acid (ALA) is a potent natural antioxidant and exhibits neuroprotective effects …
Alpha lipoic acid (ALA) is a potent natural antioxidant and exhibits neuroprotective effects …
[PDF][PDF] The effect of mirtazapine on reducing chronic stress in male rats
S Barbar Shemirani, MA Nasiri Khalili… - … Clin Neurosci J, 2022 - journals.sbmu.ac.ir
Abstract Background: Mirtazapine (Mtz) has attracted attention for its anti-anxiety properties.
We aimed to explore the impacts of chronic unpredictable stress (CUS) using Mtz treatment …
We aimed to explore the impacts of chronic unpredictable stress (CUS) using Mtz treatment …
Cashew (Anacardium occidentale) Extract: Possible Effects on Hypothalamic–Pituitary–Adrenal (HPA) Axis in Modulating Chronic Stress
GNS Désiré, FH Simplice, CW Guillaume, FZ Kamal… - Brain Sciences, 2023 - mdpi.com
Depression presents a significant global health burden, necessitating the search for effective
and safe treatments. This investigation aims to assess the antidepressant effect of the …
and safe treatments. This investigation aims to assess the antidepressant effect of the …