Big data, big knowledge: big data for personalized healthcare
M Viceconti, P Hunter, R Hose - IEEE journal of biomedical and …, 2015 - ieeexplore.ieee.org
The idea that the purely phenomenological knowledge that we can extract by analyzing
large amounts of data can be useful in healthcare seems to contradict the desire of VPH …
large amounts of data can be useful in healthcare seems to contradict the desire of VPH …
Cerebrospinal fluid mechanics and its coupling to cerebrovascular dynamics
AA Linninger, K Tangen, CY Hsu… - Annual Review of Fluid …, 2016 - annualreviews.org
Cerebrospinal fluid (CSF) is not stagnant but displays fascinating oscillatory flow patterns
inside the ventricular system and reversing fluid exchange between the cranial vault and …
inside the ventricular system and reversing fluid exchange between the cranial vault and …
Computational fluid dynamic simulation of human carotid artery bifurcation based on anatomy and volumetric blood flow rate measured with magnetic resonance …
H Gharahi, BA Zambrano, DC Zhu, JK DeMarco… - International journal of …, 2016 - Springer
Blood flow patterns and local hemodynamic parameters have been widely associated with
the onset and progression of atherosclerosis in the carotid artery. Assessment of these …
the onset and progression of atherosclerosis in the carotid artery. Assessment of these …
Engineering hydrogels for affinity-based release of therapeutic proteins
CJ Teal, SP Lu, MS Shoichet - Chemistry of Materials, 2024 - ACS Publications
Therapeutic proteins can treat a myriad of diseases; however, their effectiveness is limited
by short half-lives. Controlled release systems are advantageous because they prolong the …
by short half-lives. Controlled release systems are advantageous because they prolong the …
CNS wide simulation of flow resistance and drug transport due to spinal microanatomy
Spinal microstructures are known to substantially affect cerebrospinal fluid patterns, yet their
actual impact on flow resistance has not been quantified. Because the length scale of …
actual impact on flow resistance has not been quantified. Because the length scale of …
Translational approaches for brain delivery of biologics via cerebrospinal fluid
SS Sadekar, M Bowen, H Cai… - Clinical …, 2022 - Wiley Online Library
Delivery of biologics via cerebrospinal fluid (CSF) has demonstrated potential to access the
tissues of the central nervous system (CNS) by circumventing the blood‐brain barrier and …
tissues of the central nervous system (CNS) by circumventing the blood‐brain barrier and …
Rotating stall observations in a high speed compressor—Part I: Experimental study
J Dodds, M Vahdati - Journal of Turbomachinery, 2015 - asmedigitalcollection.asme.org
In this two-part paper, the phenomenon of part span rotating stall is studied. The objective is
to improve understanding of the physics by which stable and persistent rotating stall occurs …
to improve understanding of the physics by which stable and persistent rotating stall occurs …
[HTML][HTML] Altered diastolic flow patterns and kinetic energy in subtle left ventricular remodeling and dysfunction detected by 4D flow MRI
E Svalbring, A Fredriksson, J Eriksson, P Dyverfeldt… - PloS one, 2016 - journals.plos.org
Aims 4D flow magnetic resonance imaging (MRI) allows quantitative assessment of left
ventricular (LV) function according to characteristics of the dynamic flow in the chamber …
ventricular (LV) function according to characteristics of the dynamic flow in the chamber …
[HTML][HTML] A 3D subject-specific model of the spinal subarachnoid space with anatomically realistic ventral and dorsal spinal cord nerve rootlets
Background The spinal subarachnoid space (SSS) has a complex 3D fluid-filled geometry
with multiple levels of anatomic complexity, the most salient features being the spinal cord …
with multiple levels of anatomic complexity, the most salient features being the spinal cord …
[HTML][HTML] The impact of spinal cord nerve roots and denticulate ligaments on cerebrospinal fluid dynamics in the cervical spine
S Heidari Pahlavian, T Yiallourou, RS Tubbs… - PloS one, 2014 - journals.plos.org
Cerebrospinal fluid (CSF) dynamics in the spinal subarachnoid space (SSS) have been
thought to play an important pathophysiological role in syringomyelia, Chiari I malformation …
thought to play an important pathophysiological role in syringomyelia, Chiari I malformation …