Biological aging profoundly impairs the homeostasis of the skeletal system. Cellular
senescence, a hallmark of biological aging, plays an instrumental role in bone disease. The …

Mitochondria in osteoblasts have been demonstrated to play multiple crucial functions in
bone formation from intracellular ATP production to extracellular secretion of mitochondrial …

Background: Osteoporosis is an important medical and social public health problem in an
aging or elderly society. Osteoporosis is caused by an imbalance in bone remodeling, which …

Osteoporosis is a chronic disease that seriously affects the quality of life and longevity of the
elderly, so exploring the mechanism of osteoporosis is crucial for drug development and …

The MC3T3-E1 preosteoblastic cell line is widely utilised as a reliable in vitro system to
assess bone formation. However, the experimental growth conditions for these cells hugely …

Актуальность: Остеопороз является важной медицинской и социальной проблемой
общественного здравоохранения в стареющем или пожилом обществе. Остеопороз …

Purpose Steroid-induced osteonecrosis of the femoral head (SONFH) is a refractory
orthopedic hip joint disease that primarily affects middle-aged and young individuals …

Polystyrene microplastics (mic‐PS) have become harmful pollutants that attracted
substantial attention about their potential toxicity. Hydrogen sulfide (H2S) is the third …

Obesity has become a worldwide epidemic accompanied by adverse health effects. The
limited efficiency of traditional weight reduction regimens has led to a substantial increase in …