Global prevalence and clinical characteristics of metabolic-associated fatty liver disease: a meta-analysis and systematic review of 10 739 607 individuals

KE Chan, TJL Koh, ASP Tang, J Quek… - The Journal of …, 2022 - academic.oup.com
Abstract Background and Aims Metabolic-associated fatty liver disease (MAFLD) was
proposed as a better definition of nonalcoholic fatty liver disease (NAFLD) to encompass the …

Perspectives on precision medicine approaches to NAFLD diagnosis and management

A Lonardo, JP Arab, M Arrese - Advances in Therapy, 2021 - Springer
Precision medicine defines the attempt to identify the most effective approaches for specific
subsets of patients based on their genetic background, clinical features, and environmental …

Once-weekly subcutaneous semaglutide improves fatty liver disease in patients with type 2 diabetes: a 52-week prospective real-life study

S Volpe, G Lisco, M Fanelli, D Racaniello, V Colaianni… - Nutrients, 2022 - mdpi.com
Background. Nonalcoholic fatty liver disease (NAFLD) is commonly observed in patients
with type 2 diabetes (T2D). Semaglutide, a glucagon-like peptide 1 receptor agonist, may …

Natural polyphenols in metabolic syndrome: protective mechanisms and clinical applications

S Zhang, M Xu, W Zhang, C Liu, S Chen - International journal of …, 2021 - mdpi.com
Metabolic syndrome (MetS) is a chronic disease, including abdominal obesity, dyslipidemia,
hyperglycemia, and hypertension. It should be noted that the occurrence of MetS is closely …

[HTML][HTML] Effect of cofactors on NAFLD/NASH and MAFLD. A paradigm illustrating the pathomechanics of organ dysfunction

A Lonardo, AK Singal, N Osna… - Metabolism and target …, 2022 - ncbi.nlm.nih.gov
Primary nonalcoholic fatty liver disease (NAFLD) is bi-directionally associated with the
metabolic syndrome and its constitutive features (“factors”: impaired glucose disposal …

The effects of eight weeks' very low-calorie ketogenic diet (VLCKD) on liver health in subjects affected by overweight and obesity

R Rinaldi, S De Nucci, F Castellana, M Di Chito… - Nutrients, 2023 - mdpi.com
Very low-calorie ketogenic diets (VLCKD) are widely employed in successful weight-loss
strategies. Herein, we evaluated the efficacy and safety of a VLCKD on non-alcoholic fatty …

Does consumption of ultra-processed foods matter for liver health? Prospective analysis among older adults with metabolic syndrome

J Konieczna, M Fiol, A Colom, MÁ Martínez-González… - Nutrients, 2022 - mdpi.com
Background Non-alcoholic fatty liver disease (NAFLD) includes a spectrum of liver
alterations that can result in severe disease and even death. Consumption of ultra …

The interplay between metabolic dysregulations and non-alcoholic fatty liver disease in women after menopause

R Robeva, D Mladenović, M Vesković, D Hrnčić… - Maturitas, 2021 - Elsevier
The hypoestrogenic period after menopause and associated metabolic imbalance might
facilitate the onset of non-alcoholic fatty liver disease (NAFLD) and its progression. The …

Metabolic-associated fatty liver disease is highly prevalent in the postacute COVID syndrome

J Milic, S Barbieri, L Gozzi, A Brigo… - Open Forum …, 2022 - academic.oup.com
Background A proposal has recently been advanced to change the traditional definition of
nonalcoholic fatty liver disease to metabolic-associated fatty liver disease (MAFLD), to reflect …

[PDF][PDF] The Fatty liver Index (FLI) 15 years later: A reappraisal

A Lonardo, S Ballestri, G Bedogni… - Metab Target Organ …, 2021 - academia.edu
Abstract The Fatty Liver Index (FLI) is a non-invasive biomarker proposed, in 2006, by
Bedogni's group, to aid in identifying patients with suspected nonalcoholic fatty liver disease …