Diabetic kidney disease (DKD) has become the leading cause of end-stage renal disease
(ESRD), and the prevalence of DKD has increased worldwide during recent years. DKD is …

Diabetic kidney disease (DKD) is a common complication in patients with diabetes mellitus
(DM). Increasing evidence suggested that the gut microbiota participates in the progression …

Background Diabetic nephropathy (DN) is one of the most common diabetic complications,
which has become the primary cause of end-stage renal disease (ESRD) globally …

Diabetic kidney disease (DKD) is the principal culprit behind chronic kidney disease (CKD),
ultimately developing end-stage renal disease (ESRD) and necessitating costly dialysis or …

Regulatory T cells (Tregs) have critical roles in maintaining immune hemostasis and have
important anti-inflammatory functions in diseases. Recently, we identified that CX-5461 (a …

Abstract Aims/Introduction Different types of diabetes show distinct genetic characteristics,
but the specific genetic susceptibility factors remain unclear. Our study aimed to explore the …

To control immune responses, regulatory CD4+ CD25+ Foxp3+ T cells (Treg) maintain their
wide and diverse repertoire through continuous arrival of recent thymic emigrants (RTE) …

Severe inflammatory response and functional impairment of endothelial progenitor cells
(EPCs) often lead to the implantation failure of EPC-captured tissue engineered blood …

In arterial hypertension, increased Th17 cells and reduced Tregs are the hallmarks of
immunological dysfunction and the basis for the investigation of immunomodulatory drugs …

Objective: Type 2 diabetes mellitus (T2DM) is a complex polygenic disease. The onset of the
disease is related to autoimmunity. However, how immune cells function in the peripheral …