The nucleus pulposus (NP), a heterogeneous tissue, is an essential functional component of
the intervertebral disc. However, NP cell development route and regulation mechanism in …

This Perspective adapts the ViolEx Model, a framework validated in several clinical
conditions, to better understand the role of expectations in the recovery and/or maintenance …

Molecular understanding of osteoarthritis (OA) has greatly increased over the past 15 years
through careful analysis of tissue samples, pre-clinical models and large-scale agnostic '∼ …

Most of us have read publications where the introduction includes a statistic from one of the
Global Burden of Disease (GBD) studies. 1 2 We may be told that musculoskeletal …

Globally, mental and musculoskeletal disorders present with high prevalence, disease
burden, and comorbidity. In order to improve the quality of care for patients with persistent …

Aim To estimate the age-standardized incidence, prevalence, and mortality rates of
autoimmune diseases including rheumatoid arthritis (RA), inflammatory bowel disease …

Purpose The paper aims to provide the main principles and practical aspects of the model,
to present the process of identifying, determining the level, as well as assessing and …

Objective To quantify the burden of osteoarthritis (OA) associated with high body mass index
(BMI) across 204 countries and territories from 1990 to 2019. Methods This study extracted …

Gout, the most prevalent inflammatory arthritis, is becoming increasingly prevalent in the
United States and across the world, and it adversely impacts people's quality of life and their …

Objectives To provide an overview and indepth analysis of temporal trends in prevalence of
musculoskeletal (MSK) disorders in women of childbearing age (WCBA) at global, regional …