Immunotherapy is the new trend in cancer treatment due to the selectivity, long lasting
effects, and demonstrated improved overall survival and tolerance, when compared to …

Despite advances in the development of clinical agents for treating Mantle Cell Lymphoma
(MCL), treatment of MCL remains a challenge due to complexity and frequent relapse …

Background Exosomes derived from tumor cells (TEXs) are involved in both immune
suppression, angiogenesis, metastasis and anticancer stimulatory, but the biological …

Background: Radiofrequency ablation (RFA) is an established treatment option for
malignancies located in the liver. RFA-induced irreversible coagulation necrosis leads to the …

To determine the contribution of skin DC subsets in the regulation of humoral immunity, we
used a well-characterized antigen targeting system to limit antigen availability and …

Immunotherapy against cancer and infectious disease holds the promise of high efficacy
with minor side effects. Mucosal vaccines to protect against tumors or infections disease …

We compared the HIV-1-specific immune responses generated by targeting HIV-1 envelope
protein (Env gp140) to either CD40 or LOX-1, two endocytic receptors on dendritic cells …

Vaccines represent the discovery of utmost importance for global health, due to both
prophylactic action to prevent infections and therapeutic intervention in neoplastic diseases …

ABSTRACT Cyclin dependent kinase 4/6 inhibitors (CDK4/6i) lead to cell-cycle arrest but
also trigger T cell-mediated immunity, which might be mediated by changes in human …

Hematological malignancies manifest as lymphoma, leukemia, and myeloma, and remain a
burden on society. From initial therapy to endless relapse-related treatment, societal burden …