Osteoarthritis (OA) is a highly prevalent chronic joint disease and the leading cause of
disability. Currently, no drugs are available to control joint damage or ease the associated …

Metabolic stress induced by high-fat (HF) diet leads to cognitive dysfunction and aging, but
the physiological mechanisms are not fully understood. Senescence-accelerated prone …

Background and purpose—Charcot neuropathy is characterized by bone destruction in a
foot leading to deformity, instability, and risk of amputation. Little is known about the …

Objective We previously suggested that fibroblast‐rich granulation tissue eroding the
subchondral bone is instrumental in the joint remodeling that occurs in ankylosing …

Abstract Background Long noncoding RNAs (lncRNAs) are recently found to be critical
regulators of the epigenome. However, our knowledge of their role in osteoarthritis (OA) …

Endometriosis is one of the most common gynecological diseases that adversely effects the
lives of women. Our previous studies showed that LINC01541 plays a key role in 17β …

Phosphate (P) is an essential element involved in various biological actions, such as bone
integrity, energy production, cell signaling and molecular component. P homeostasis is …

Although previous studies have implicated pro-inflammatory cytokines, such as tumor
necrosis factor-α (TNF-α) and interleukin-6 (IL-6), to be detrimental for osteogenic activity …

Osteoderms are bony plates found in the skin of vertebrates, mostly commonly in reptiles
where they have evolved independently multiple times, suggesting the presence of a gene …

Introduction In ankylosing spondylitis (AS), joint remodeling leading to joint ankylosis
involves cartilage fusion. Here, we analyzed whether chondrocyte hypertrophy is involved in …