The microbiota-gut-brain axis in sleep disorders

Z Wang, Z Wang, T Lu, W Chen, W Yan, K Yuan… - Sleep medicine …, 2022 - Elsevier
Sleep is a complex physiological process and is a critical determinant of physical and
mental health. In the past decades, significant progress has been made in understanding …

The circadian regulation of food intake

E Challet - Nature Reviews Endocrinology, 2019 - nature.com
Feeding, which is essential for all animals, is regulated by homeostatic mechanisms. In
addition, food consumption is temporally coordinated by the brain over the circadian (~ 24 h) …

Revisiting the role of neurotransmitters in epilepsy: An updated review

E Akyuz, AK Polat, E Eroglu, I Kullu, E Angelopoulou… - Life sciences, 2021 - Elsevier
Epilepsy is a neurologicaldisorder characterized by persistent predisposition to recurrent
seizurescaused by abnormal neuronal activity in the brain. Epileptic seizures maydevelop …

[HTML][HTML] Histidine metabolism and function

ME Brosnan, JT Brosnan - The Journal of Nutrition, 2020 - Elsevier
Histidine is a dietary essential amino acid because it cannot be synthesized in humans. The
WHO/FAO requirement for adults for histidine is 10 mg· kg body weight-1· d-1. Histidine is …

Conducting polymer-based electrochemical biosensors for neurotransmitters: A review

JM Moon, N Thapliyal, KK Hussain, RN Goyal… - Biosensors and …, 2018 - Elsevier
Neurotransmitters are important biochemical molecules that control behavioral and
physiological functions in central and peripheral nervous system. Therefore, the analysis of …

International union of basic and clinical pharmacology. XCVIII. Histamine receptors

P Panula, PL Chazot, M Cowart, R Gutzmer… - Pharmacological …, 2015 - ASPET
Histamine is a developmentally highly conserved autacoid found in most vertebrate tissues.
Its physiological functions are mediated by four 7-transmembrane G protein–coupled …

Control of sleep and wakefulness

RE Brown, R Basheer, JT McKenna… - Physiological …, 2012 - journals.physiology.org
This review summarizes the brain mechanisms controlling sleep and wakefulness.
Wakefulness promoting systems cause low-voltage, fast activity in the …

Imidazole: synthesis, functionalization and physicochemical properties of a privileged structure in medicinal chemistry

HV Tolomeu, CAM Fraga - Molecules, 2023 - mdpi.com
Imidazole was first synthesized by Heinrich Debus in 1858 and was obtained by the reaction
of glyoxal and formaldehyde in ammonia, initially called glyoxaline. The current literature …

[HTML][HTML] Current enlightenment about etiology and pharmacological treatment of autism spectrum disorder

N Eissa, M Al-Houqani, A Sadeq, SK Ojha… - Frontiers in …, 2018 - frontiersin.org
Autistic Spectrum Disorder (ASD) is a complex neurodevelopmental brain disorder
characterized by two core behavioral symptoms, namely impairments in social …

Control of synaptic plasticity in deep cortical networks

PR Roelfsema, A Holtmaat - Nature Reviews Neuroscience, 2018 - nature.com
Humans and many other animals have an enormous capacity to learn about sensory stimuli
and to master new skills. However, many of the mechanisms that enable us to learn remain …