Exercise is the real polypill

C Fiuza-Luces, N Garatachea, NA Berger… - Physiology, 2013 - journals.physiology.org
The concept of a “polypill” is receiving growing attention to prevent cardiovascular disease.
Yet similar if not overall higher benefits are achievable with regular exercise, a drug-free …

[PDF][PDF] Pericytes: developmental, physiological, and pathological perspectives, problems, and promises

A Armulik, G Genové, C Betsholtz - Developmental cell, 2011 - cell.com
Pericytes, the mural cells of blood microvessels, have recently come into focus as regulators
of vascular morphogenesis and function during development, cardiovascular homeostasis …

Mesenchymal stem cell–based tissue regeneration is governed by recipient T lymphocytes via IFN-γ and TNF-α

Y Liu, L Wang, T Kikuiri, K Akiyama, C Chen, X Xu… - Nature medicine, 2011 - nature.com
Stem cell–based regenerative medicine is a promising approach in tissue reconstruction.
Here we show that proinflammatory T cells inhibit the ability of exogenously added bone …

The immunomodulatory capacity of mesenchymal stem cells

A Gebler, O Zabel, B Seliger - Trends in molecular medicine, 2012 - cell.com
Mesenchymal stem cells (MSCs) are currently being tested in clinical trials for the treatment
of various diseases owing to the ease of generating and expanding these cells, the ability to …

Malignant tumor formation after transplantation of short-term cultured bone marrow mesenchymal stem cells in experimental myocardial infarction and diabetic …

JO Jeong, JW Han, JM Kim, HJ Cho, C Park… - Circulation …, 2011 - Am Heart Assoc
Rationale: Bone marrow (BM)–derived mesenchymal stem cells (MSCs) hold great promise
for cardiovascular cell therapy owing to their multipotency and culture expandability …

A prospective, non-randomized, no placebo-controlled, phase Ib clinical trial to study the safety of the adipose derived stromal cells-stromal vascular fraction in …

A Tzouvelekis, V Paspaliaris, G Koliakos… - Journal of translational …, 2013 - Springer
Introduction Regenerative medicine and particular adult stem cells represent an alternative
option with several fruitful therapeutic applications in patients suffering from chronic lung …

Influence of decellularized matrix derived from human mesenchymal stem cells on their proliferation, migration and multi-lineage differentiation potential

H Lin, G Yang, J Tan, RS Tuan - Biomaterials, 2012 - Elsevier
Developing biomaterials to promote stem cell proliferation and differentiation is a critical
requirement in tissue engineering and regeneration. Extracellular matrix (ECM) derived from …

Regeneration of dental pulp following pulpectomy by fractionated stem/progenitor cells from bone marrow and adipose tissue

R Ishizaka, K Iohara, M Murakami, O Fukuta… - Biomaterials, 2012 - Elsevier
Pulp stem/progenitor cells can induce complete pulp regeneration. However, due to the
limited availability of pulp tissue with age, there is a need to examine other sources for …

Stem cell treatment for patients with autoimmune disease by systemic infusion of culture-expanded autologous adipose tissue derived mesenchymal stem cells

JC Ra, SK Kang, IS Shin, HG Park, SA Joo… - Journal of translational …, 2011 - Springer
Prolonged life expectancy, life style and environmental changes have caused a changing
disease pattern in developed countries towards an increase of degenerative and …

Periodontal regeneration using a xenogeneic bone substitute seeded with autologous periodontal ligament‐derived mesenchymal stem cells: A 12‐month quasi …

N Sánchez, L Fierravanti, J Núñez… - Journal of clinical …, 2020 - Wiley Online Library
Aim To evaluate the safety and efficacy of autologous periodontal ligament‐derived
mesenchymal stem cells (PDL‐MSCs) embedded in a xenogeneic bone substitute (XBS) for …