[HTML][HTML] Metformin, macrophage dysfunction and atherosclerosis
Metformin is one of the most widely prescribed hypoglycemic drugs and has the potential to
treat many diseases. More and more evidence shows that metformin can regulate the …
treat many diseases. More and more evidence shows that metformin can regulate the …
Immunotherapy discovery on tumor organoid-on-a-chip platforms that recapitulate the tumor microenvironment
Cancer immunotherapy has achieved remarkable success over the past decade by
modulating patients' own immune systems and unleashing pre-existing immunity. However …
modulating patients' own immune systems and unleashing pre-existing immunity. However …
[HTML][HTML] Recent advances in mRNA cancer vaccines: meeting challenges and embracing opportunities
B Wang, J Pei, S Xu, J Liu, J Yu - Frontiers in immunology, 2023 - frontiersin.org
Since the successful application of messenger RNA (mRNA) vaccines in preventing COVID-
19, researchers have been striving to develop mRNA vaccines for clinical use, including …
19, researchers have been striving to develop mRNA vaccines for clinical use, including …
SingPro: a knowledge base providing single-cell proteomic data
Single-cell proteomics (SCP) has emerged as a powerful tool for detecting cellular
heterogeneity, offering unprecedented insights into biological mechanisms that are masked …
heterogeneity, offering unprecedented insights into biological mechanisms that are masked …
[HTML][HTML] Spatial transcriptomics technology in cancer research
In recent years, spatial transcriptomics (ST) technologies have developed rapidly and have
been widely used in constructing spatial tissue atlases and characterizing spatiotemporal …
been widely used in constructing spatial tissue atlases and characterizing spatiotemporal …
[HTML][HTML] Cytotoxic T-lymphocyte antigen-4 in colorectal cancer: another therapeutic side of capecitabine
A Derakhshani, S Hashemzadeh, Z Asadzadeh… - Cancers, 2021 - mdpi.com
Simple Summary Colorectal cancer (CRC) begins when normal cells turn out of balance,
and a tumor is formed in the lining of the colon or rectum. Cytotoxic T-lymphocyte protein 4 …
and a tumor is formed in the lining of the colon or rectum. Cytotoxic T-lymphocyte protein 4 …
Understanding initiation and progression of hepatocellular carcinoma through single cell sequencing
XY Li, Y Shen, L Zhang, X Guo, J Wu - Biochimica et Biophysica Acta (BBA) …, 2022 - Elsevier
Unsatisfied clinical outcome drives to better understand hepatic carcinogenesis,
microenvironment and escape of immune surveillance in hepatocellular carcinoma (HCC) …
microenvironment and escape of immune surveillance in hepatocellular carcinoma (HCC) …
[HTML][HTML] Therapeutic cancer vaccines revamping: technology advancements and pitfalls
Highlights•CVs have been characterized by positive safety and immunogenicity profiles but
low levels of clinical efficacy.•Novel CV strategies entail personalized formulations and …
low levels of clinical efficacy.•Novel CV strategies entail personalized formulations and …
[HTML][HTML] Phenomic studies on diseases: potential and challenges
W Ying - Phenomics, 2023 - Springer
The rapid development of such research field as multi-omics and artificial intelligence (AI)
has made it possible to acquire and analyze the multi-dimensional big data of human …
has made it possible to acquire and analyze the multi-dimensional big data of human …
[HTML][HTML] Nanoformulations targeting immune cells for cancer therapy: mRNA therapeutics
W Yang, J Cao, H Cheng, L Chen, M Yu, Y Chen… - Bioactive Materials, 2023 - Elsevier
The approved worldwide use of two messenger RNA (mRNA) vaccines (BNT162b2 and
mRNA-1273) in late 2020 has proven the remarkable success of mRNA therapeutics …
mRNA-1273) in late 2020 has proven the remarkable success of mRNA therapeutics …