Introduction Current multistep methods utilized for preparing and cryopreserving single-cell
suspensions from blood samples for single-cell RNA sequencing (scRNA-seq) are time …

The prevalence of diabetes is consistently rising worldwide. Diabetic nephropathy is a
leading cause of chronic renal failure. The present study aimed to explore the crosstalk …

Translational research plays a key role in drug development and biomarker discovery for
hepatocellular carcinoma (HCC). However, unique challenges exist in this field because of …

The global increase in cancer incidence presents significant economic and societal
challenges. While chimeric antigen receptor-modified T cell (CAR-T) therapy has …

Tumor immune microenvironment (TIME) consists of intra-tumor immunological components
and plays a significant role in tumor initiation, progression, metastasis, and response to …

Extranodal natural killer/T‐cell lymphoma (NKTCL) is an aggressive type of lymphoma
associated with Epstein–Barr virus (EBV) and characterized by heterogeneous tumor …

Lung cancer patients tend to have strong intratumoral and intertumoral heterogeneity and
complex tumor microenvironment, which are major contributors to the efficacy of and drug …

Random forest (RF) is a widely used data prediction and variable selection technique.
However, the variable selection aspect of RF can become unreliable when there are more …

Simple Summary The development of targeted therapies has led to personalized medicine
for advanced non-small cell lung cancer (NSCLC), particularly in lung adenocarcinoma …

Purpose Pancreatic adenocarcinoma (PAAD) is characterized by low antitumour immune
cell infiltration in an immunosuppressive microenvironment. This study aimed to …