[HTML][HTML] Epigallocatechin-3-Gallate (EGCG): New therapeutic perspectives for neuroprotection, aging, and neuroinflammation for the modern age

A Payne, S Nahashon, E Taka, GM Adinew… - Biomolecules, 2022 - mdpi.com
Alzheimer's and Parkinson's diseases are the two most common forms of neurodegenerative
diseases. The exact etiology of these disorders is not well known; however, environmental …

[HTML][HTML] Mitochondrial dysfunction in Parkinson's disease: from mechanistic insights to therapy

XY Gao, T Yang, Y Gu, XH Sun - Frontiers in aging neuroscience, 2022 - frontiersin.org
Parkinson's disease (PD) is one of the most common neurodegenerative movement
disorders worldwide. There are currently no cures or preventative treatments for PD …

[HTML][HTML] Allicin, an antioxidant and neuroprotective agent, ameliorates cognitive impairment

MS Nadeem, I Kazmi, I Ullah, K Muhammad, F Anwar - Antioxidants, 2021 - mdpi.com
Allicin (diallylthiosulfinate) is a defense molecule produced by cellular contents of garlic
(Allium sativum L.). On tissue damage, the non-proteinogenic amino acid alliin (S …

[HTML][HTML] Non-invasive photobiomodulation treatment in an Alzheimer Disease-like transgenic rat model

L Yang, C Wu, E Parker, Y Li, Y Dong, L Tucker… - Theranostics, 2022 - ncbi.nlm.nih.gov
Alzheimer's disease (AD) is the most common form of dementia in the elderly, causing
neuronal degeneration and cognitive deficits that significantly impair independence and …

[HTML][HTML] Dl-3-n-butylphthalide rescues dopaminergic neurons in Parkinson's disease models by inhibiting the NLRP3 inflammasome and ameliorating mitochondrial …

R Que, J Zheng, Z Chang, W Zhang, H Li, Z Xie… - Frontiers in …, 2021 - frontiersin.org
Background Neuroinflammation and mitochondrial impairment play important roles in the
neuropathogenesis of Parkinson's disease (PD). The activation of NLRP3 inflammasome …

[HTML][HTML] Neurodegeneration and neuroinflammation in Parkinson's disease: a self-sustained loop

G Arena, K Sharma, G Agyeah, R Krüger… - Current Neurology and …, 2022 - Springer
Abstract Purpose of Review Neuroinflammation plays a significant role in Parkinson's
disease (PD) etiology along with mitochondrial dysfunction and impaired proteostasis. In this …

[HTML][HTML] Brain alarm by self-extracellular nucleic acids: From neuroinflammation to neurodegeneration

R Kunze, S Fischer, HH Marti, KT Preissner - Journal of Biomedical …, 2023 - Springer
Neurological disorders such as stroke, multiple sclerosis, as well as the neurodegenerative
diseases Parkinson's or Alzheimer's disease are accompanied or even powered by danger …

The role of mitochondrial dysfunction in periodontitis: From mechanisms to therapeutic strategy

W Jiang, Y Wang, Z Cao, Y Chen, C Si… - Journal of …, 2023 - Wiley Online Library
Periodontitis is an inflammatory and destructive disease of tooth‐supporting tissue and has
become the leading cause of adult tooth loss. The most central pathological features of …

[HTML][HTML] The potential for mitochondrial therapeutics in the treatment of primary open-angle glaucoma: a review

G Kuang, M Halimitabrizi, AA Edziah, R Salowe… - Frontiers in …, 2023 - frontiersin.org
Glaucoma, an age-related neurodegenerative disease, is characterized by the death of
retinal ganglion cells (RGCs) and the corresponding loss of visual fields. This disease is the …

[HTML][HTML] Interaction between autophagy and the NLRP3 inflammasome in Alzheimer's and Parkinson's disease

R Lu, L Zhang, X Yang - Frontiers in Aging Neuroscience, 2022 - frontiersin.org
Autophagy degrades phagocytosed damaged organelles, misfolded proteins, and various
pathogens through lysosomes as an essential way to maintain cellular homeostasis …