Diseases of the cardiovascular system that cause sudden cardiac deaths are often caused
by lethal arrhythmias that originate from defects in the cardiac conduction system …

Sinoatrial node (SAN) disease mechanisms are poorly understood, and therapeutic options
are limited. Natriuretic peptide (s)(NP) are cardioprotective hormones whose effects can be …

The sinoatrial node (SAN), the primary pacemaker of the heart, consists of a heterogeneous
population of specialized cardiac myocytes that can spontaneously produce action …

Aims The sinus venous myocardium, comprising the sinoatrial node (SAN) and sinus horns
(SH), is a region subject to congenital malformations and cardiac arrhythmias. It …

Physiological systems vary in a day-night manner anticipating increased demand at a
particular time. Heart is no exception. Cardiac output is primarily determined by heart rate …

We investigated the role of podoplanin in development of the sinus venosus myocardium
comprising the sinoatrial node, dorsal atrial wall, and primary atrial septum as well as the …

The sinoatrial node (SAN), the primary cardiac pacemaker, consists of a head domain and a
junction/tail domain that exhibit different functional properties. However, the underlying …

The sinoatrial node (SAN) is the dominant pacemaker of the heart. Abnormalities in SAN
formation and function can cause sinus arrhythmia, including sick sinus syndrome and …

BACKGROUND AND PURPOSE Recent clinical data suggest beneficial effects of
ivabradine, a specific heart rate (HR)‐lowering drug, in heart failure patients. However, the …

Fluorescent immunohistochemistry on the cardiac conduction system in whole mount mouse
heart preparations demonstrates a particularly dense and complex network of nerve fibres …