[HTML][HTML] The temporal variation in the effects of extreme temperature on respiratory mortality: Evidence from 136 cities in China, 2006–2019

J Qi, J Zhang, Y Wang, J Huang, O Aboubakri… - Environment …, 2024 - Elsevier
Background In the context of climate change and urbanization, the temporal variation of the
adverse health effect of extreme temperature has attracted increasing attention. Methods …

PECAM-1 mediates temsirolimus-induced increase in neutrophil transendothelial migration that leads to lung injury

X Chen, J Chen, S Liu, X Li - Biochemical and Biophysical Research …, 2023 - Elsevier
Temsirolimus is a first-generation mTOR inhibitor commonly used in the clinical treatment of
cancers that is associated with lung injury. However, the mechanism underlying this adverse …

Destruction of vascular endothelial glycocalyx during formation of pre-metastatic niches

R Qu, W Du, S Li, W Li, G Wei, Z Chen, H Gao, S Shi… - Heliyon, 2024 - cell.com
A special microenvironment called the" pre-metastatic niche" is thought to help primary
tumor cells migrate to new tissues and invade them, in part because the normal barrier …

The Pulmonary Endothelial Glycocalyx Modifications in Glypican 1 Knockout Mice Do Not Affect Lung Endothelial Function in Physiological Conditions

LNR Thota, JE Lopez Rosales, I Placencia… - International Journal of …, 2023 - mdpi.com
The endothelial glycocalyx is a dynamic signaling surface layer that is involved in the
maintenance of cellular homeostasis. The glycocalyx has a very diverse composition, with …

Down‐regulating lncRNA KCNQ1OT1 relieves type II alveolar epithelial cell apoptosis during one‐lung ventilation via modulating miR‐129‐5p/HMGB1 axis induced …

Z Song, Z Wang, J Cai, Y Zhou, Y Jiang… - Environmental …, 2024 - Wiley Online Library
Objective Endothelial glycocalyx (EG) maintains vascular homeostasis and is destroyed
after one‐lung ventilation (OLV)‐induced lung injury. Long noncoding RNAs (lncRNAs) are …

Hydrogen prevents lipopolysaccharide-induced pulmonary microvascular endothelial cell injury by inhibiting store-operated Ca2+ entry regulated by STIM1/Orai1

Y Li, H Chen, R Shu, X Zhang, G Wang, Y Yin - Shock, 2023 - journals.lww.com
Background Sepsis is a type of life-threatening organ dysfunction that is caused by a
dysregulated host response to infection. The lung is the most vulnerable target organ under …