Nature has abundant source of drugs that need to be identified/purified for use as essential
biologics, either individually or in combination in the modern medical field. These drugs are …

Plant bioactive molecules could play key preventive and therapeutic roles in chronological
aging and the pathogenesis of many chronic diseases, often accompanied by increased …

Background Genkwanin is a flavone isolated from the traditional Chinese herb Daphne
genkwa. Our previous work proved that four flavonoids (including genkwanin) isolated from …

Abstract Aflatoxin B 1 (AFB 1) is the most hazardous aflatoxin that causes significant
damage to the male reproductive system. Genkwanin (GNK) is a bioactive flavonoid that …

Purpose The aim of the present study was to develop an optimized Genkwanin (GKA)-
loaded self-nanoemulsifying drug delivery system (SNEDDS) formulation to enhance the …

Flavonoids are polyphenols frequently consumed in the diet they have been suggested to
exert a number of beneficial actions on human health, including anti-inflammatory activity …

Background Cytochrome P450 monooxygenase constitutes a significant group of oxidative
enzymes that can introduce an oxygen atom in a high regio-and stereo-selectivity mode. We …

Apigenin is a kind of flavonoid with many beneficial biological effects. It not only has direct
cytotoxicity to tumor cells, but also can boost the antitumor effect of immune cells by …

Colorectal adenoma (CRA) is a premalignant lesion of colorectal cancer. The current
treatment is surgical resection, but CRA is prone to recurrence, and there is no safe and …

The COVID-19 pandemic has inflicted millions of deaths worldwide. Despite the availability
of several vaccines and some special drugs approved for emergency use to prevent or treat …