Investigating toxin diversity and abundance in snake venom proteomes

T Tasoulis, TL Pukala, GK Isbister - Frontiers in Pharmacology, 2022 - frontiersin.org
Understanding snake venom proteomes is becoming increasingly important to understand
snake venom biology, evolution and especially clinical effects of venoms and approaches to …

Cerebral complications of snakebite envenoming: case studies

YK Huang, YC Chen, CC Liu, HC Cheng, AT Tu… - Toxins, 2022 - mdpi.com
There are an estimated 5.4 million snakebite cases every year. People with snakebite
envenoming suffer from severe complications, or even death. Although some review articles …

High-throughput proteomics and in vitro functional characterization of the 26 medically most important elapids and vipers from sub-Saharan Africa

GTT Nguyen, C O'Brien, Y Wouters, L Seneci… - …, 2022 - academic.oup.com
Venomous snakes are important parts of the ecosystem, and their behavior and evolution
have been shaped by their surrounding environments over the eons. This is reflected in their …

[HTML][HTML] Interpopulational variation and ontogenetic shift in the venom composition of Lataste's viper (Vipera latastei, Boscá 1878) from northern Portugal

I Avella, JJ Calvete, L Sanz, W Wüster, F Licata… - Journal of …, 2022 - Elsevier
Lataste's viper (Vipera latastei) is a venomous European viper endemic to the Iberian
Peninsula, recognised as medically important by the World Health Organization. To date, no …

[HTML][HTML] Analytical strategies in venomics

J Slagboom, C Kaal, A Arrahman, FJ Vonk… - Microchemical …, 2022 - Elsevier
Snakebite envenoming is a major issue in certain developing parts of the world, with tens of
thousands of deaths and a multitude of lingering permanent medical conditions on a yearly …

Modern venomics—Current insights, novel methods, and future perspectives in biological and applied animal venom research

BM von Reumont, G Anderluh, A Antunes… - …, 2022 - academic.oup.com
Venoms have evolved> 100 times in all major animal groups, and their components, known
as toxins, have been fine-tuned over millions of years into highly effective biochemical …

Quantification of snake venom proteomes by mass spectrometry‐considerations and perspectives

JJ Calvete, B Lomonte, AJ Saviola… - Mass Spectrometry …, 2023 - Wiley Online Library
The advent of soft ionization mass spectrometry‐based proteomics in the 1990s led to the
development of a new dimension in biology that conceptually allows for the integral analysis …

Venomous bites, stings and poisoning by European vertebrates as an overlooked and emerging medical problem: recognition, clinical aspects and therapeutic …

G Paolino, MR Di Nicola, I Avella, SR Mercuri - Life, 2023 - mdpi.com
Europe presents a high number of venomous and poisonous animals able to elicit medically
relevant symptoms in humans. However, since most of the accidents involving venomous or …

A review of the proteomic profiling of African Viperidae and Elapidae snake venoms and their antivenom neutralisation

BC Offor, B Muller, LA Piater - Toxins, 2022 - mdpi.com
Snakebite envenoming is a neglected tropical disease (NTD) that results from the injection
of snake venom of a venomous snake into animals and humans. In Africa (mainly in sub …

One Size Fits All—Venomics of the Iberian Adder (Vipera seoanei, Lataste 1878) Reveals Low Levels of Venom Variation across Its Distributional Range

I Avella, M Damm, I Freitas, W Wüster, N Lucchini… - Toxins, 2023 - mdpi.com
European vipers (genus Vipera) are medically important snakes displaying considerable
venom variation, occurring at different levels in this group. The presence of intraspecific …