Glyphosate, a non-selective systemic biocide with broad-spectrum activity, is the most widely
used herbicide in the world. It can persist in the environment for days or months, and its …

Glial cell-derived neurotrophic factor (GDNF), and the neurotrophin nerve growth factor
(NGF) and brain-derived neurotrophic factor (BDNF) are important for the survival …

Background & Aims Probiotics can reduce symptoms of irritable bowel syndrome (IBS), but
little is known about their effects on psychiatric comorbidities. We performed a prospective …

Our team has been a pioneer in harvesting extracellular vesicles (EVs) enriched for
neuronal origin from peripheral blood and using them as a biomarker discovery platform for …

Over 60 million people worldwide are diagnosed with glaucomatous optic neuropathy,
which is estimated to be responsible for 8.4 million cases of irreversible blindness globally …

The natural polyamine spermidine and spermine have been reported to ameliorate aging
and aging-induced dementia. However, the mechanism is still confused. An aging model …

Physical exercise may improve cognitive function by modulating molecular and cellular
mechanisms within the brain. We propose that the facilitation of long-term synaptic …

Background The study of clinically related biological indicators in Major Depression (MD) is
important. The Brain Derived Neurotrophic Factor (BDNF) appears to play an important role …

Purpose: Depression is one of the most prevalent, recurrent and life-threatening mental
illnesses. However, the precise mechanism underlying the disorder is not yet clearly …

Alzheimer's disease (AD) is the most common form of dementia affecting people mainly in
their sixth decade of life and at a higher age. It is an extensively studied neurodegenerative …