In vivo imaging technologies have emerged as a powerful tool for both fundamental
research and clinical practice. In particular, luminescence imaging in the tissue-transparent …

Bone healing is associated with many orthopedic conditions, including fractures and
osteonecrosis, arthritis, metabolic bone disease, tumors and periprosthetic particle …

Periodontium supports teeth in a mechanically stimulated tissue environment, where
heterogenous stem/progenitor populations contribute to periodontal homeostasis. In this …

We describe a general approach to produce bone and cartilaginous structures utilizing the
self-regenerative capacity of the intercostal rib space to treat a deformed …

Fat graft is widely used in plastic and reconstructive surgery. The size of the injectable
product, the unpredictable fat resorption rates, and subsequent adverse effects make it tricky …

Recent studies have revealed the vital role of MSCs in bone regeneration. In both self-
healing bone regeneration processes and biomaterial-induced healing of bone defects …

In growing children, growth plate cartilage has limited self-repair ability upon fracture injury
always leading to limb growth arrest. Interestingly, one type of fracture injuries within the …

Stem cells remain in a quiescent state for long-term maintenance and preservation of
potency; this process requires fine-tuning regulatory mechanisms. In this study, we identified …

Abstract Background Skeletal Stem Cells (SSCs) are required for skeletal development,
homeostasis, and repair. The perspective of their wide application in regenerative medicine …

Trauma rapidly mobilizes the immune response of surrounding tissues and activates
regeneration program. Manipulating immune response to promote tissue regeneration …