Simple Summary Granulomatosis is commonly observed in patients receiving immune
checkpoint inhibitors (ICIs) for melanoma and other cancers. Recognizing this reaction early …

Foxp3+ regulatory T cells (Tregs) are potent suppressor cells, essential for the maintenance
of immune homeostasis. Most Tregs develop in the thymus and are then released into the …

Sarcoidosis is a chronic granulomatous disorder characterized by an accumulation of T
lymphocytes, macrophages, and immune-effector cells within affected organs. The …

Objective Chronic pancreatitis (CP) is a potentially fatal disease of the exocrine pancreas,
with no specific or effective approved therapies. Due to difficulty in accessing pancreas …

CC chemoattractant cytokine (chemokine) receptor 6 (CCR6) and its exclusive binding
molecule CCL20 is an extremely important chemokine receptor-ligand pair which controls …

Background: Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease of unknown origin,
with a median patient survival time of~ 3 years after diagnosis without anti-fibrotic therapy. It …

Aims Improvement of clinical diagnostics of idiopathic giant cell myocarditis (IGCM) and
cardiac sarcoidosis (CS), two frequently fatal human myocardial diseases. Currently, IGCM …

Abstract Tuberculosis-causing Mycobacterium tuberculosis (Mtb) is transmitted via airborne
droplets followed by a primary infection of macrophages and dendritic cells. During the …

Role of imbalance between Th17 and regulatory T-cells in sar... : Current Opinion in Pulmonary
Medicine Role of imbalance between Th17 and regulatory T-cells in sarcoidosis : Current …

Background Traumatic brain injury (TBI) is a major cause of death and disability in the USA
and the world; it constitutes 30% of injury-related deaths (Taylor et al., MMWR Surveill …