The C–C motif ligand 20 (CCL20) is a chemokine that specifically binds to the chemokine
receptor 6 (CCR6) and the CCL20/CCR6 axis has been implicated in the non-small lung …

While gaining interest as treatment for cancer and infectious disease, the clinical efficacy of
Vγ9Vδ2 T cell-based immunotherapeutics has to date been limited. An improved …

A functional polymorphism within butyrophilin-like 2 (BTNL2) gene has been described as a
potential risk factor for sarcoidosis. The association between chronicity and the rs2076530 …

Introduction: Sarcoidosis is a multi-systemic granulomatous disease of unknown aetiology.
Ethnicity and environmental factors may influence disease incidence, phenotype and …

Sarcoidosis is a multisystemic granulomatous inflammation associated with Th17/regulatory
T cell (Treg) polarization. As a marker of inflammation, serum amyloid A (SAA) could …

α1-Antitrypsin (AAT) acts as an important neutrophil elastase inhibitor in the lung. Although
the hepatocyte is considered to be the primary source of AAT, local production by …

Sarcoidosis is a multi-organ granulomatous inflammatory disease of unknown etiology. Over
50% of patients will require treatment at some point in their disease and 10%–30% will …

Sarcoidosis is a multi-organ disorder where immunology, genetic and environmental factors
play a key role in causing Sarcoidosis, but its molecular mechanism remains unclear …

Sarcoidosis is an inflammatory granulomatous disease with unknown etiology driven by
cytokines and chemokines. There is limited information regarding the regulation of …

Aims: The diagnostic approach to idiopathic giant-cell myocarditis (IGCM) is based on
identifying various patterns of inflammatory cell infiltration and multinucleated giant cells …