Pathophysiology of coronary artery disease

P Libby, P Theroux - Circulation, 2005 - Am Heart Assoc
During the past decade, our understanding of the pathophysiology of coronary artery
disease (CAD) has undergone a remarkable evolution. We review here how these advances …

Do plaques rapidly progress prior to myocardial infarction? The interplay between plaque vulnerability and progression

A Ahmadi, J Leipsic, R Blankstein, C Taylor… - Circulation …, 2015 - Am Heart Assoc
There is a common misperception in the cardiology community that most acute coronary
events arise from ruptures of mildly stenotic plaques. This notion has emanated from …

ACC/AHA guidelines for coronary angiography: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines …

PJ Scanlon, DP Faxon, AM Audet, B Carabello… - Journal of the American …, 1999 - jacc.org
The ACC/AHA Task Force on Practice Guidelines herein revises and updates the original
“Guidelines for Coronary Angiography,” published in 1987 (1). The frequent and still …

Relation of the site of acute myocardial infarction to the most severe coronary arterial stenosis at prior angiography

D Giroud, JM Li, P Urban, B Meier… - The American journal of …, 1992 - Elsevier
To determine whether the site of acute myocardial infarction (AMI) can be predicted on the
basis of a previous coronary angiogram, 184 consecutive angiograms obtained between …

Structure-dependent dynamic mechanical behavior of fibrous caps from human atherosclerotic plaques.

RT Lee, AJ Grodzinsky, EH Frank, RD Kamm… - Circulation, 1991 - Am Heart Assoc
BACKGROUND Although thrombosis associated with a fissured atherosclerotic plaque is
believed to be the most common cause of acute coronary syndromes, the underlying factors …

Stranger in a strange land: the pathogenesis of saphenous vein graft stenosis with emphasis on structural and functional differences between veins and arteries

JL Cox, DA Chiasson, AI Gotlieb - Progress in cardiovascular diseases, 1991 - Elsevier
The USE OF saphenous vein grafts (SVG) in coronary artery bypass graft (CABG) surgery is
the mainstay of the surgical treatment of ischemic heart disease. lm3 Less than 3% of …

Morphologic features of unstable atherothrombotic plaques underlying acute coronary syndromes

E Falk - The American journal of cardiology, 1989 - Elsevier
Unstable angina appears to be a good clinical marker for rapidly progressing coronary
artery disease. Pathologically, an unstable atherothrombotic coronary lesion, represented by …

Effects of monotherapy with an HMG-CoA reductase inhibitor on the progression of coronary atherosclerosis as assessed by serial quantitative arteriography. The …

D Waters, L Higginson, P Gladstone, B Kimball… - Circulation, 1994 - Am Heart Assoc
BACKGROUND 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors are widely
prescribed for hyperlipidemia, yet their effect on the evolution of coronary atherosclerosis …

Process of progression of coronary artery lesions from mild or moderate stenosis to moderate or severe stenosis: a study based on four serial coronary arteriograms …

K Yokoya, H Takatsu, T Suzuki, H Hosokawa, S Ojio… - Circulation, 1999 - Am Heart Assoc
Background—The process of progression in coronary artery disease is unknown. Methods
and Results—The subjects were 36 patients with 36 objective vessels with clinically …

Prognostic significance of progression of coronary atherosclerosis.

D Waters, TE Craven, J Lesperance - Circulation, 1993 - Am Heart Assoc
BACKGROUND Angiographic progression of coronary atherosclerosis is frequently
observed in clinical practice and is used as an end point in clinical trials; however, its …