Cancer is one of the leading causes of death worldwide, and the factors responsible for its
progression need to be elucidated. Exosomes are structures with an average size of 100 nm …

Interleukins and associated cytokines serve as the means of communication for innate and
adaptive immune cells as well as non-immune cells and tissues. Thus, interleukins have a …

Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic systemic
inflammation causing progressive joint damage that can lead to lifelong disability. The …

Several immune and immunocompetent cells, including dendritic cells, macrophages,
adipocytes, natural killer cells, T cells, and B cells, are significantly correlated with the …

Macrophages represent heterogeneous cell population with important roles in defence
mechanisms and in homoeostasis. Tissue macrophages from diverse anatomical locations …

Introduction Inflammation is a defensive response of the organism to irritation which is
manifested by redness, swelling, heat, pain and dysfunction. The inflammatory response …

Neutrophils, the most abundant innate immune cells, function as crucial regulators of the
adaptive immune system in diverse pathological conditions, including metastatic cancer …

Chronic kidney disease (CKD) affects many adults worldwide. Persistent low-grade
inflammation is a substantial factor in its development and progression and has correlated …

Abnormal activation of the gut mucosal immune system and a highly dysregulated gut
microbiota play essential roles in the progression of inflammatory bowel disease (IBD). The …

STAT proteins represent an important family of evolutionarily conserved transcription factors
that play key roles in diverse biological processes, notably including blood and immune cell …