The stringent response is a stress signalling system mediated by the alarmones guanosine
tetraphosphate (ppGpp) and guanosine pentaphosphate (pppGpp) in response to nutrient …

Biofilms are surface-attached groups of microbial cells encased in an extracellular matrix
that are significantly less susceptible to antimicrobial agents than non-adherent, planktonic …

Bacterial persister cells are phenotypic variants that exhibit a transient non-growing state
and antibiotic tolerance. Here, we provide in vitro evidence of Staphylococcus aureus …

The formation of multicellular microbial communities, called biofilms, starts from the
adhesion of a few planktonic cells to the surface. The transition from a free-living planktonic …

Networks of molecular regulators are often the primary objects of focus in the study of gene
regulation, with the machinery of protein synthesis tacitly relegated to the background …

BACKGROUND The escalating crisis of multidrug resistance is raising fears of untreatable
infections caused by bacterial “superbugs.” However, many patients already suffer from …

Quorum sensing (QS) is a communication mechanism between bacteria that allows specific
processes to be controlled, such as biofilm formation, virulence factor expression, production …

Bacterial attachment to biomaterials is of great interest to the medical and dental field due to
its impact on dental implants, dental prostheses, and others, leading to the need to introduce …

Gene expression in bacteria relies on promoter recognition by the DNA-dependent RNA
polymerase and subsequent transcription initiation. Bacterial cells are able to tune their …

Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …